CDC73 and TSGA10

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		CDC73	TSGA10
Description		cell division cycle 73	testis specific 10
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Cytosol Cdc73/Paf1 Complex	Cellular_component Cytoplasm Centriole Sperm Fibrous Sheath Neuron Projection Sperm Principal Piece
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding	Molecular_function Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Endodermal Cell Fate Commitment Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Polyadenylation Cell Cycle Negative Regulation Of Cell Proliferation Histone Monoubiquitination Wnt Signaling Pathway Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of MRNA 3'-end Processing Protein Destabilization Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2B Ubiquitination Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex Negative Regulation Of Apoptotic Process Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Cellular Response To Lipopolysaccharide Positive Regulation Of Cell Cycle G1/S Phase Transition Beta-catenin-TCF Complex Assembly Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Spermatogenesis Cell Projection Assembly
Pathways		Formation of RNA Pol II elongation complex Formation of the beta-catenin:TCF transactivating complex Hedgehog 'on' state RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins
Drugs
Diseases		Primary hyperparathyroidism; Familial hyperparathyroidism (HRPT)
GWAS		Chronotype ( 30696823) Ovarian disease with few adhesions ( 28333195) Photic sneeze reflex ( 27182965) Subcutaneous adipose tissue ( 22589738) Takayasu arteritis ( 25604533) White matter hyperintensity burden ( 25663218)	Bipolar disorder ( 21926972) Intelligence (MTAG) ( 29326435)
Interacting Genes		30 interacting genes: ALAS1 ANXA6 CEP70 CTNNB1 DDAH2 FAF1 FSD2 GC GOLGA2 H1-2 HAP1 HSF2BP HSPA4 ITFG1 KASH5 KCNH2 KIAA1549 KIDINS220 MCM3AP MTUS2 MYC PITHD1 RNF40 TCEA1 TCF4 TFCP2 TOMM20 TSGA10 VPS37B WWC1	42 interacting genes: AXIN1 BCL6B BIRC2 CBX8 CBY2 CCDC33 CCHCR1 CDC73 CDK18 CEP44 CEP57L1 CREB5 FAM161A FBF1 GCC2-AS1 HIF1A KRT6A LMNA MID2 PPHLN1 PPP1R18 PRPF31 RCOR3 RNF6 RTP5 SCEL SYT6 TCEA2 TLE5 TRIM29 ZBTB24 ZBTB38 ZNF124 ZNF2 ZNF410 ZNF417 ZNF426 ZNF490 ZNF544 ZNF587 ZNF599 ZNF670
Entrez ID		79577	80705
HPRD ID		09581	06202
Ensembl ID		ENSG00000134371	ENSG00000135951
Uniprot IDs		Q6P1J9	A0A218MIY9 Q9BZW7
PDB IDs		5YDE 5YDF
Enriched GO Terms of Interacting Partners?
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