CDC73 and GOLGA2

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		CDC73	GOLGA2
Description		cell division cycle 73	golgin A2
Image
GO Annotations	Cellular Component	Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Cytosol Cdc73/Paf1 Complex	Golgi Cis Cisterna Golgi Membrane Spindle Pole Golgi Apparatus Cis-Golgi Network Microtubule COPII-coated ER To Golgi Transport Vesicle Golgi Cisterna Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Mitotic Spindle
	Molecular Function	RNA Polymerase II Complex Binding Protein Binding	Protein Binding Microtubule Binding Protein Kinase Binding Syntaxin Binding Identical Protein Binding Cadherin Binding Importin-alpha Family Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cell Growth Endodermal Cell Fate Commitment Transcription By RNA Polymerase II Transcription Elongation From RNA Polymerase II Promoter MRNA Polyadenylation Cell Cycle Negative Regulation Of Cell Proliferation Histone Monoubiquitination Wnt Signaling Pathway Protein Ubiquitination Stem Cell Population Maintenance Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of MRNA 3'-end Processing Protein Destabilization Positive Regulation Of Transcription Elongation From RNA Polymerase II Promoter Histone H2B Ubiquitination Recruitment Of 3'-end Processing Factors To RNA Polymerase II Holoenzyme Complex Negative Regulation Of Apoptotic Process Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Fibroblast Proliferation Negative Regulation Of Epithelial Cell Proliferation Cellular Response To Lipopolysaccharide Positive Regulation Of Cell Cycle G1/S Phase Transition Beta-catenin-TCF Complex Assembly Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle	Protein Glycosylation ER To Golgi Vesicle-mediated Transport Microtubule Nucleation Golgi Organization Centrosome Cycle Asymmetric Cell Division Negative Regulation Of Autophagy Protein Transport Negative Regulation Of Protein Binding COPII Vesicle Coating Spindle Assembly Protein Homotetramerization Positive Regulation Of Protein Glycosylation Golgi Ribbon Formation Golgi Disassembly Spindle Assembly Involved In Meiosis Mitotic Spindle Assembly Positive Regulation Of Ubiquitin Protein Ligase Activity
Pathways		Formation of RNA Pol II elongation complex Formation of the beta-catenin:TCF transactivating complex Hedgehog 'on' state RNA Polymerase II Pre-transcription Events RNA Polymerase II Transcription Elongation E3 ubiquitin ligases ubiquitinate target proteins	Golgi Cisternae Pericentriolar Stack Reorganization Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models
Drugs
Diseases		Primary hyperparathyroidism; Familial hyperparathyroidism (HRPT)
GWAS		Chronotype ( 30696823) Ovarian disease with few adhesions ( 28333195) Photic sneeze reflex ( 27182965) Subcutaneous adipose tissue ( 22589738) Takayasu arteritis ( 25604533) White matter hyperintensity burden ( 25663218)	Body mass index ( 26426971)
Interacting Genes		30 interacting genes: ALAS1 ANXA6 CEP70 CTNNB1 DDAH2 FAF1 FSD2 GC GOLGA2 H1-2 HAP1 HSF2BP HSPA4 ITFG1 KASH5 KCNH2 KIAA1549 KIDINS220 MCM3AP MTUS2 MYC PITHD1 RNF40 TCEA1 TCF4 TFCP2 TOMM20 TSGA10 VPS37B WWC1	349 interacting genes: ABHD17A ABLIM1 ADAP1 AFF4 ALKBH3 AMOTL2 ANKRD11 ANKRD36BP1 APC ARID5A ARL16 ARL4A ARNT2 ARPC3 ATP6V1C2 ATP6V1D ATP6V1G1 ATXN7 AXIN1 BAHD1 BARD1 BCAS2 BCL6 BCL6B BMS1P1 BYSL C12orf50 C1orf109 C1orf35 C2CD6 C9orf16 CBX8 CBY2 CCAR1 CCDC146 CCDC150 CCDC17 CCDC198 CCDC70 CCDC87 CCDC92 CCHCR1 CCNC CCNH CDC20B CDC5L CDC73 CDCA7 CDK1 CDK18 CDKL3 CENPP CEP55 CEP57L1 CHCHD2 CHCHD3 CINP CKB COG6 CORO1A CRMP1 CSPP1 CSTF2T CUL5 CYB5R2 DAXX DCTN4 DCX DDX6 DEUP1 DGCR6 DLGAP5 DLX6-AS1 DMTN DNM2 DOLPP1 DTX2 DVL2 EAF2 EFHC1 EGR2 EIF3G EIF4A2 EP300 ERCC3 EXOSC5 FAM110A FAM124B FAM126B FAM161A FAM184A FAM193B FAM207A FAM214A FAM50B FAM90A1 FANCG FBF1 FBXL18 FBXO28 FIP1L1 FNDC11 GATA1 GATA2 GATAD2B GCC1 GEM GFAP GGA2 GLE1 GLYCTK GMCL1 GNG5 GORASP1 GORASP2 GPANK1 GPKOW GPS2 GRAP2 GSE1 GTPBP10 GZMA GZMK HAUS1 HDAC4 HGS HOXB9 HTRA1 HYLS1 IFT20 IFT27 IHO1 IKZF3 INPP5J IQCE ISCU ITPKB ITSN2 KANK2 KANSL1 KAT5 KDM1A KIAA1217 KIFC3 KRT18 KRT6A KRT6B KRT6C LASP1 LATS1 LCOR LCP2 LENG1 LGALS3 LHX4 LIMS2 LIN7A LINGO1 LMO1 LMO2 LMO3 LMO4 LYPLA1 LYSMD1 MAB21L2 MAGOH MAGOHB MBD3 MCM10 MCM7 MFAP1 MID2 MNAT1 MORF4L1 MORF4L2 MORN3 MOS MSRB3 MTFR2 MVP MYEF2 NCF2 NDE1 NDEL1 NDN NDUFA5 NEBL NECAB2 NEFL NME7 NMRK1 NOS3 NOTCH1 NTAQ1 NUDT21 NXT2 ODF2 ORC1 PARD6B PATL1 PCM1 PIAS2 PID1 PIK3R2 PIMREG PIN1 PITX1 PKN1 PKP4 PLAAT5 POLDIP3 POM121 PPP1R16B PPP1R18 PPP2CA PQBP1 PRKAA1 PRKAB2 PRPF31 PSMA1 PSMA4 PTBP2 PTPN11 RAB1A RAB1B RAB2A RAB2B RAB33B RAB39A RAB39B RAB6A RBL1 RBM17 RBM39 RBM41 RCOR3 RGS8 RHNO1 RIBC1 RITA1 RNF135 RNF213 RNF214 RNF6 RSPH14 RSRC2 RTP5 RUSC2 RXRB SAMD4A SAP30BP SCAF8 SCEL SCNM1 SECISBP2 SELENOV SFI1 SH2D3C SH2D4A SH3GLB2 SH3RF2 SHC3 SLU7 SMARCB1 SMARCE1 SMCP SNAP47 SNF8 SNRPB SNRPB2 SNRPC SNTA1 SNW1 SPATA2 SPATA22 SRSF2 SSX2IP STAMBPL1 STK25 STK26 STN1 SUPT5H SYT6 TBC1D22B TBP TCEA2 TCEANC TCF19 TCL1A TDP2 TEAD4 TEX9 TFAP4 TFIP11 THAP7 THYN1 TLE5 TMED2 TPM1 TPX2 TRAF1 TRAF3IP2 TRAF4 TRAF5 TRIM29 TRIM42 TSC22D4 TSSC4 TSSK3 TTC23 TTC25 TTC9C TUBGCP4 TXLNA UBE2H UBE2I UBE2U UBE3C USO1 USP2 UTP14C VPS28 VPS37C WASHC3 WT1 XIAP YJU2 YTHDC1 ZBTB16 ZER1 ZFC3H1 ZFP2 ZFYVE26 ZG16B ZGPAT ZMAT1 ZMAT2 ZNF124 ZNF250 ZNF410 ZNF414 ZNF417 ZNF488 ZNF572 ZNF581 ZNF587 ZNF594 ZNF688 ZNF774
Entrez ID		79577	2801
HPRD ID		09581	03989
Ensembl ID		ENSG00000134371	ENSG00000167110
Uniprot IDs		Q6P1J9	Q08379
PDB IDs		5YDE 5YDF	4REY 6IW8 6IWA 6K06
Enriched GO Terms of Interacting Partners?
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