LENG1 and PAK5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		LENG1	PAK5
Description		leukocyte receptor cluster member 1	p21 (RAC1) activated kinase 5
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nucleoplasm Cytoplasm Mitochondrion Synapse
	Molecular Function	Molecular_function Protein Binding	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding
	Biological Process	Biological_process	Regulation Of Cell Growth Apoptotic Process Cytoskeleton Organization Signal Transduction Regulation Of Mitotic Cell Cycle Learning Memory Locomotory Behavior Cell Proliferation Cell Migration Signal Transduction By Protein Phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Negative Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways			Activation of RAC1
Drugs
Diseases
GWAS		Pre-treatment viral load in HIV-1 infection ( 31219150)	Atopy ( 28927820) Plasma factor V levels in venous thrombosis (conditioned on rs6027) ( 31271701)
Interacting Genes		36 interacting genes: APP BANP CALCOCO2 CARD9 CBY2 CCDC102B CCDC136 CCDC57 CDR2 CEP57L1 CEP70 FSD2 GOLGA2 KASH5 KIFC3 KLF10 KRT31 KRT40 LDOC1 MID2 MTUS2 NAB2 NAGK NECAB2 OSGEP PAK5 PDE4DIP PNMA1 ROPN1 STX11 TCF4 TFIP11 TMEM239 TRIM27 TRIM54 USHBP1	21 interacting genes: ARMC7 ATPAF2 BAD CARD9 CCNG1 CDC42 CRBN EMD EXOSC1 FHL3 GCC1 INKA1 LENG1 LZTS2 PDLIM7 PRPF31 PSMF1 RAC1 SORBS3 TUBGCP4 UXT
Entrez ID		79165	57144
HPRD ID		13985	06423
Ensembl ID		ENSG00000105617	ENSG00000101349
Uniprot IDs		Q96BZ8	B0AZM9 Q9P286
PDB IDs			2F57
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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