GNPTAB and ZNF250

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		GNPTAB	ZNF250
Description		N-acetylglucosamine-1-phosphate transferase subunits alpha and beta	zinc finger protein 250
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Integral Component Of Membrane	Nucleus
	Molecular Function	UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase Activity Calcium Ion Binding Protein Binding	DNA Binding Metal Ion Binding
	Biological Process	Lysosome Organization N-glycan Processing To Lysosome Secretion Of Lysosomal Enzymes Carbohydrate Phosphorylation	Regulation Of Transcription, DNA-templated
Pathways			Generic Transcription Pathway
Drugs
Diseases		Mucolipidosis II and III, including: Mucolipidosis II / I-cell disease; Mucolipidosis III A / Pseudo-Hurler polydystrophy; Mucolipidosis III C
GWAS		Blood protein levels ( 29875488 28240269) Bone mineral density (total hip) ( 29883787)	Logical memory (immediate recall) in normal cognition ( 29274321)
Interacting Genes		8 interacting genes: AEN APP DISC1 FAM90A1 MAPK1 PSMA1 STAMBPL1 ZNF250	47 interacting genes: BEGAIN CARD9 CCDC102B CCDC136 CCDC85B CDCA7L CEP44 DPPA2 DVL2 FAM124A GMCL1 GNPTAB GOLGA2 HEXIM2 HOOK1 HOOK2 KASH5 KRT40 KRTAP10-3 KRTAP10-7 KRTAP4-12 LDOC1 LZTS2 MAGOHB MID2 MTUS2 NINL PLEKHF2 PRPF31 SSX2IP SYNE4 TFF1 TMCC2 TNNT1 TNS2 TRAF1 TRIM23 TRIM27 TRIM41 TRIM54 UBE3A ZBTB8A ZC4H2 ZNF165 ZNF175 ZNF460 ZNF473
Entrez ID		79158	58500
HPRD ID		11350	15758
Ensembl ID		ENSG00000111670	ENSG00000196150
Uniprot IDs		Q3T906	B3KNS9 P15622
PDB IDs		2N6D
Enriched GO Terms of Interacting Partners?
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