SCNM1 and TRIM37

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		SCNM1	TRIM37
Description		sodium channel modifier 1	tripartite motif containing 37
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Speck	Cytoplasm Peroxisome Cytosol Aggresome ESC/E(Z) Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Enzyme Binding Metal Ion Binding	Chromatin Binding Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity
	Biological Process	Alternative MRNA Splicing, Via Spliceosome RNA Splicing	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of NF-kappaB Transcription Factor Activity Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination Negative Regulation Of Centriole Replication Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Aggresome Assembly
Pathways			Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS			Cognitive function ( 25644384) General cognitive ability ( 29844566) Testicular germ cell tumor ( 23666239)
Interacting Genes		48 interacting genes: BLZF1 CBY2 CCDC33 CCDC85B CDR2 CEP44 COG6 DVL2 GOLGA2 HMG20A IKZF1 INCA1 KRT31 KRT38 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 LNX2 LZTS2 MCM6 MEOX2 MID2 MIPOL1 MKRN3 MTUS2 NAB2 NOTCH2NLA PDE4DIP PLSCR1 PNMA1 PNMA2 PRNP RINT1 RPGRIP1 SSX2IP SYCE1 TFIP11 TLE5 TRAF1 TRIM27 TRIM37 TRIM42 TRIM54 UBXN11 ZBTB14 ZDHHC17	63 interacting genes: ANKRD11 APEX2 APTX ARNT2 AXIN1 BYSL CCDC33 CDC20B CDK5RAP2 COPB1 CWF19L2 DDX6 DLGAP5 ELOA2 EWSR1 FAM107A FAM124B FAM161A FAM50B FXR2 H2AC20 H2AC4 IKBKG KAT5 KIAA0408 KIF9 LTBR MAGEB18 MCM10 MCRS1 NGFR NUDT18 PBK PNKP PRC1 RASD1 RHPN1 RIBC2 RNF6 RPL9 RXRB SCNM1 TNFRSF1B TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 UBASH3A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U ZMAT2 ZNF329 ZNF417 ZNF655
Entrez ID		79005	4591
HPRD ID		12162	05463
Ensembl ID		ENSG00000163156	ENSG00000108395
Uniprot IDs		Q9BWG6	O94972
PDB IDs			3LRQ
Enriched GO Terms of Interacting Partners?
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