TRIM37 and ZMAT2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TRIM37	ZMAT2
Description		tripartite motif containing 37	zinc finger matrin-type 2
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GO Annotations	Cellular Component	Cytoplasm Peroxisome Cytosol Aggresome ESC/E(Z) Complex Perinuclear Region Of Cytoplasm	Nucleus U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome
	Molecular Function	Chromatin Binding Ubiquitin-protein Transferase Activity Tumor Necrosis Factor Receptor Binding Protein Binding Zinc Ion Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Protein Ligase Activity	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of NF-kappaB Transcription Factor Activity Histone H2A Monoubiquitination Histone H2A-K119 Monoubiquitination Negative Regulation Of Centriole Replication Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of NF-kappaB Transcription Factor Activity Protein Autoubiquitination Aggresome Assembly	MRNA Splicing, Via Spliceosome
Pathways		Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Cognitive function ( 25644384) General cognitive ability ( 29844566) Testicular germ cell tumor ( 23666239)	Major depressive disorder ( 27479909) Schizophrenia ( 28991256 29483656) Systolic blood pressure ( 30224653)
Interacting Genes		63 interacting genes: ANKRD11 APEX2 APTX ARNT2 AXIN1 BYSL CCDC33 CDC20B CDK5RAP2 COPB1 CWF19L2 DDX6 DLGAP5 ELOA2 EWSR1 FAM107A FAM124B FAM161A FAM50B FXR2 H2AC20 H2AC4 IKBKG KAT5 KIAA0408 KIF9 LTBR MAGEB18 MCM10 MCRS1 NGFR NUDT18 PBK PNKP PRC1 RASD1 RHPN1 RIBC2 RNF6 RPL9 RXRB SCNM1 TNFRSF1B TRAF1 TRAF2 TRAF3 TRAF4 TRAF5 TRAF6 UBASH3A UBB UBE2D1 UBE2D2 UBE2D3 UBE2E1 UBE2E2 UBE2E3 UBE2H UBE2U ZMAT2 ZNF329 ZNF417 ZNF655	25 interacting genes: AK8 AMH CBY2 CCDC57 CEP76 FSD2 FXR2 GOLGA2 HMBOX1 IKZF1 KRT40 LZTS2 MEOX2 MTUS2 PHC2 SPAG5 SSX2IP TFEC TFIP11 TRAF2 TRIM36 TRIM37 VPS52 ZBTB14 ZBTB8A
Entrez ID		4591	153527
HPRD ID		05463	08094
Ensembl ID		ENSG00000108395	ENSG00000146007
Uniprot IDs		O94972	Q96NC0
PDB IDs		3LRQ	5O9Z 6AHD
Enriched GO Terms of Interacting Partners?
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