PRR14 and CBX5

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (two hybrid)

		PRR14	CBX5
Description		proline rich 14	chromobox 5
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Lamina Nucleoplasm Chromosome	Histone Deacetylase Complex Kinetochore Nuclear Chromosome, Telomeric Region Nucleus Nuclear Envelope Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Nucleolus Chromocenter PML Body Transcriptional Repressor Complex Nuclear Pericentric Heterochromatin Protein-containing Complex Histone Methyltransferase Complex Site Of DNA Damage Ribonucleoprotein Complex
	Molecular Function	Protein Binding	Chromatin Binding Protein Binding Protein Binding, Bridging Methylated Histone Binding Identical Protein Binding Histone Deacetylase Binding Ribonucleoprotein Complex Binding Protein-containing Complex Binding Repressing Transcription Factor Binding
	Biological Process	Muscle Organ Development	Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Blood Coagulation Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition
Pathways			SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6 Factors involved in megakaryocyte development and platelet production
Drugs			Copper
Diseases
GWAS		Immunoglobulin light chain (AL) amyloidosis ( 28025584) Irritable mood ( 29500382) Neurociticism ( 29500382)	Alcohol consumption ( 31358974) Blood protein levels ( 30072576) Hip circumference ( 28552196) Mean platelet volume ( 22139419) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: APP CBX5 DCTPP1 SH3BP4 SH3GL2	55 interacting genes: ARHGDIA ARL5A BAP1 BARD1 BCL11B BRCA1 CBX1 CBX3 CHAF1A DNMT3B DSN1 ELOA2 ELOC FSHR GOLGA8EP H1-4 H1-5 H2AW H2BU1 H3-4 H3C15 H4-16 HDAC4 HDAC5 HDAC9 HECW2 INCENP LBR LRIF1 MBD1 MCC MIS12 MKI67 NIPBL NR2F1 NSD3 NSL1 PRR14 RPSA SMARCA4 SP1 SP100 SRPK1 SRPK2 STAM2 SUB1 SUV39H1 TAF4 TRIM24 TRIM28 UBE2A UBE2B VPS28 XRCC6 XRN1
Entrez ID		78994	23468
HPRD ID		14541	05131
Ensembl ID		ENSG00000156858	ENSG00000094916
Uniprot IDs		A0A024QZB5 Q9BWN1	P45973 V9HWG0
PDB IDs			3FDT 3I3C
Enriched GO Terms of Interacting Partners?
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