CBX5 and H2AW

Number of citations of the paper that reports this interaction (PubMedID 11336697)
139

Data Source:
BioGRID (pull down)

		CBX5	H2AW
Description		chromobox 5	H2A.W histone
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Kinetochore Nuclear Chromosome, Telomeric Region Nucleus Nuclear Envelope Nucleoplasm Nuclear Heterochromatin Pericentric Heterochromatin Nucleolus Chromocenter PML Body Transcriptional Repressor Complex Nuclear Pericentric Heterochromatin Protein-containing Complex Histone Methyltransferase Complex Site Of DNA Damage Ribonucleoprotein Complex	Nuclear Nucleosome Nuclear Chromatin Extracellular Exosome
	Molecular Function	Chromatin Binding Protein Binding Protein Binding, Bridging Methylated Histone Binding Identical Protein Binding Histone Deacetylase Binding Ribonucleoprotein Complex Binding Protein-containing Complex Binding Repressing Transcription Factor Binding	DNA Binding Protein Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cellular Response To DNA Damage Stimulus Blood Coagulation Viral Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of G0 To G1 Transition	Chromatin Organization Nucleosome Disassembly Chromatin Silencing UV-damage Excision Repair
Pathways		SUMOylation of chromatin organization proteins Transcriptional Regulation by E2F6 Factors involved in megakaryocyte development and platelet production	HDACs deacetylate histones HATs acetylate histones HATs acetylate histones RMTs methylate histone arginines UCH proteinases Ub-specific processing proteases Metalloprotease DUBs HCMV Early Events HCMV Late Events
Drugs		Copper
Diseases
GWAS		Alcohol consumption ( 31358974) Blood protein levels ( 30072576) Hip circumference ( 28552196) Mean platelet volume ( 22139419) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		55 interacting genes: ARHGDIA ARL5A BAP1 BARD1 BCL11B BRCA1 CBX1 CBX3 CHAF1A DNMT3B DSN1 ELOA2 ELOC FSHR GOLGA8EP H1-4 H1-5 H2AW H2BU1 H3-4 H3C15 H4-16 HDAC4 HDAC5 HDAC9 HECW2 INCENP LBR LRIF1 MBD1 MCC MIS12 MKI67 NIPBL NR2F1 NSD3 NSL1 PRR14 RPSA SMARCA4 SP1 SP100 SRPK1 SRPK2 STAM2 SUB1 SUV39H1 TAF4 TRIM24 TRIM28 UBE2A UBE2B VPS28 XRCC6 XRN1	5 interacting genes: CBX5 DNTTIP2 KRTAP10-3 RPS6KA5 TCL1A
Entrez ID		23468	92815
HPRD ID		05131	13660
Ensembl ID		ENSG00000094916	ENSG00000181218
Uniprot IDs		P45973 V9HWG0	Q7L7L0
PDB IDs		3FDT 3I3C
Enriched GO Terms of Interacting Partners?
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