CACNA1E and EFHC1

Number of citations of the paper that reports this interaction (PubMedID 15258581)
57

Data Source:
HPRD (in vivo, in vitro)

		CACNA1E	EFHC1
Description		calcium voltage-gated channel subunit alpha1 E	EF-hand domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Synapse	Spindle Pole Centrosome Axoneme Neuronal Cell Body Mitotic Spindle
	Molecular Function	Voltage-gated Calcium Channel Activity Calcium Ion Binding Voltage-gated Cation Channel Activity	Calcium Ion Binding Protein Binding Protein C-terminus Binding Alpha-tubulin Binding
	Biological Process	Calcium Ion Transport Chemical Synaptic Transmission Regulation Of Ion Transmembrane Transport Regulation Of Insulin Secretion Membrane Depolarization Calcium Ion Import Calcium Ion Transmembrane Transport	Mitotic Cytokinesis Mitotic Spindle Organization Cerebral Cortex Cell Migration Regulation Of Cell Division Cilium-dependent Cell Motility
Pathways		Presynaptic depolarization and calcium channel opening Regulation of insulin secretion
Drugs
Diseases			Idiopathic generalied epilepsies (IGEs), including: Childhood absence epilepsy (CAE); Juvenile absence epilepsy (JAE); Juvenile myoclonic epilepsy (JME); Epilepsy with generalized tonic-clonic seizures alone
GWAS		Body mass index (change over time) ( 25378290) Coronary artery calcification ( 23870195) Feeling hurt ( 29500382) Height ( 31562340) Intelligence (MTAG) ( 29326435) Lumbar spine bone mineral density (integral) ( 27476799) Neuroticism ( 29255261) Presence of antiphospholipid antibodies ( 27098658)	Atopic march ( 26542096) Mean platelet volume ( 27863252) Perceived intensity of glucose ( 31005972) Post bronchodilator FEV1/FVC ratio in COPD ( 26634245)
Interacting Genes		2 interacting genes: EFHC1 HSPA1A	18 interacting genes: CACNA1E DOK7 EFHC2 EIF4ENIF1 GOLGA2 HOMER3 IHO1 IKZF3 KCTD4 KRT15 REL RIMBP3 SH3GLB2 TCF4 TEX11 TRAF2 TRIP6 ZBED1
Entrez ID		777	114327
HPRD ID		03006	10583
Ensembl ID		ENSG00000198216	ENSG00000096093
Uniprot IDs		Q15878 Q59FG1	B2CKC5 Q5JVL4
PDB IDs		3BXL
Enriched GO Terms of Interacting Partners?
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