ZBTB17 and ITGB5

Number of citations of the paper that reports this interaction (PubMedID 12356872)
32

Data Source:
HPRD (two hybrid)

		ZBTB17	ITGB5
Description		zinc finger and BTB domain containing 17	integrin subunit beta 5
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Protein-containing Complex Protein-DNA Complex	Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Integrin Alphav-beta5 Complex Receptor Complex Phagocytic Vesicle Extracellular Exosome
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Core Promoter Binding Transcription Coactivator Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Metal Ion Binding	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity
	Biological Process	Gastrulation With Mouth Forming Second Ectoderm Development Negative Regulation Of Cell Proliferation IRE1-mediated Unfolded Protein Response Negative Regulation Of Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Cell Cycle Arrest	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Muscle Contraction Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Migration Extracellular Matrix Organization Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Stress Fiber Assembly Viral Entry Into Host Cell Epithelial Cell-cell Adhesion
Pathways		XBP1(S) activates chaperone genes	Cross-presentation of particulate exogenous antigens (phagosomes) Molecules associated with elastic fibres Integrin cell surface interactions Integrin cell surface interactions Syndecan interactions Syndecan interactions ECM proteoglycans Smooth Muscle Contraction
Drugs
Diseases
GWAS		Erectile dysfunction ( 30583798) Glomerular filtration rate ( 29403010) Heel bone mineral density ( 30598549) Idiopathic dilated cardiomyopathy ( 21459883)	Airway hyperresponsiveness ( 23984888) Carpal tunnel syndrome ( 30833571) Coronary artery disease ( 28714974) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		24 interacting genes: BCL6 CDKN2B CREBBP DIS3 DNMT3A E2F6 EP300 ESR1 ESR2 GTF2I HCFC1 HK2 HK3 HSPB1 IRF8 ITGB5 MAX MSX2 MYC MYCN PGR TMPRSS11A TOPBP1 ZBTB7C	36 interacting genes: ANXA5 CCN1 DAB1 DAB2 DOK1 EHMT2 EPS8 EWSR1 FHL2 FLNA ITGA5 ITGAV ITGB3BP KRT40 KRTAP10-8 KRTAP10-9 LTBP1 LTBP3 MTDH MTUS2 MYO10 NOTCH2NLA NUMB P2RY2 PAK4 PALLD PPARD PTK2 RACK1 SNTA1 SPP1 SRSF9 STAB2 TLN1 TNS2 ZBTB17
Entrez ID		7709	3693
HPRD ID		04968	00949
Ensembl ID		ENSG00000116809	ENSG00000082781
Uniprot IDs		Q13105 Q53EM1	D3DNA1 L7RT22 P18084
PDB IDs		2LVR 2LVT 2LVU 2M0D 2M0E 2M0F 2N25 2N26 2Q81 3M52 4U2M 4U2N 5ION
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?