ITGB5 and ITGB3BP

Number of citations of the paper that reports this interaction (PubMedID 10579726)
7

Data Source:
HPRD (in vivo)

		ITGB5	ITGB3BP
Description		integrin subunit beta 5	integrin subunit beta 3 binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Focal Adhesion Integrin Complex Cell Surface Integrin Alphav-beta5 Complex Receptor Complex Phagocytic Vesicle Extracellular Exosome	Condensed Chromosome Kinetochore Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Virus Receptor Activity Integrin Binding Protein Binding Signaling Receptor Activity	Protein Binding Protein C-terminus Binding
	Biological Process	Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Muscle Contraction Cell-matrix Adhesion Transforming Growth Factor Beta Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Migration Extracellular Matrix Organization Cell Adhesion Mediated By Integrin Endodermal Cell Differentiation Stress Fiber Assembly Viral Entry Into Host Cell Epithelial Cell-cell Adhesion	Regulation Of Transcription, DNA-templated Apoptotic Process Cell Cycle Cell Adhesion Signal Transduction CENP-A Containing Nucleosome Assembly Positive Regulation Of Apoptotic Process Cell Division
Pathways		Cross-presentation of particulate exogenous antigens (phagosomes) Molecules associated with elastic fibres Integrin cell surface interactions Integrin cell surface interactions Syndecan interactions Syndecan interactions ECM proteoglycans Smooth Muscle Contraction	Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal NRIF signals cell death from the nucleus NRIF signals cell death from the nucleus Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Airway hyperresponsiveness ( 23984888) Carpal tunnel syndrome ( 30833571) Coronary artery disease ( 28714974) Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975) Diastolic blood pressure ( 27841878) Heel bone mineral density ( 30598549) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		36 interacting genes: ANXA5 CCN1 DAB1 DAB2 DOK1 EHMT2 EPS8 EWSR1 FHL2 FLNA ITGA5 ITGAV ITGB3BP KRT40 KRTAP10-8 KRTAP10-9 LTBP1 LTBP3 MTDH MTUS2 MYO10 NOTCH2NLA NUMB P2RY2 PAK4 PALLD PPARD PTK2 RACK1 SNTA1 SPP1 SRSF9 STAB2 TLN1 TNS2 ZBTB17	22 interacting genes: ACTN2 APP ARFIP2 CCNA2 CERT1 DDX24 ESR1 ITGB3 ITGB5 KDM1A KIFC3 LRRK2 MAPK6 MTA1 NFKB1 PIH1D2 RECQL5 RXRA RXRG SVIL THRA UBR7
Entrez ID		3693	23421
HPRD ID		00949	09267
Ensembl ID		ENSG00000082781	ENSG00000142856
Uniprot IDs		D3DNA1 L7RT22 P18084	D3DQ59 Q13352
PDB IDs
Enriched GO Terms of Interacting Partners?
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