ZNF76 and PIAS1

Number of citations of the paper that reports this interaction (PubMedID 15280358)
11

Data Source:
HPRD (two hybrid, in vitro)

		ZNF76	PIAS1
Description		zinc finger protein 76	protein inhibitor of activated STAT 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm PML Body Nuclear Speck
	Molecular Function	DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding Metal Ion Binding	RNA Polymerase II Transcription Factor Binding DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Protein C-terminus Binding Zinc Ion Binding SUMO Transferase Activity Enzyme Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Androgen Receptor Binding SUMO Ligase Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase III Positive Regulation Of Transcription By RNA Polymerase II	G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II JAK-STAT Cascade Spermatogenesis Visual Learning Protein Sumoylation Androgen Receptor Signaling Pathway Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Sumoylation Regulation Of Cell Proliferation Negative Regulation Of Apoptotic Process Fat Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Smooth Muscle Cell Differentiation Regulation Of Interferon-gamma-mediated Signaling Pathway Protein-DNA Complex Assembly
Pathways			SUMOylation of DNA damage response and repair proteins SUMOylation of transcription factors SUMOylation of ubiquitinylation proteins SUMOylation of transcription cofactors SUMOylation of intracellular receptors SUMOylation of intracellular receptors SUMOylation of chromatin organization proteins Formation of Incision Complex in GG-NER Regulation of IFNG signaling
Drugs
Diseases
GWAS		Height ( 25282103 31562340 18391951)	Diastolic blood pressure ( 30224653) Diverticular disease ( 30177863) Major depressive disorder ( 23377640) Number of twin births ( 30760885)
Interacting Genes		6 interacting genes: CSNK2B EP300 HDAC1 PIAS1 SMAD1 TBP	107 interacting genes: AKT1 AR ATXN1 AXIN1 BARD1 BRCA1 CASP8 CBS CDK4 CEBPA CEBPE CHUK CNOT7 CREB1 CREBBP CSNK2A1 CSRP2 DCLRE1A DDX21 DDX5 DNM1 DNMT3A ELK3 EP300 ESR1 ESR2 FANCI FHL3 FLI1 GATA4 GLUL GRM8 GSK3B GTF2IRD1 HECTD2 HIC1 HTT IKZF5 JUN KLF3 L3MBTL2 LSM3 MAML1 MBD1 MDC1 MDM2 MITF MSX1 MX1 MYB NCOR1 NFATC1 NIN NR2F2 NR3C2 NR5A1 PAXIP1 PGR PIAS2 PIAS4 PLAG1 PML PPP1CA PPP1CC PRDM1 PRPF40A PSME3 PTK2 PTPN1 QKI RAD54L2 RBBP6 RELA SATB1 SATB2 SERBP1 SGTA SKIL SMAD1 SMAD4 SMAD7 SNAI2 SNIP1 SP3 SPOP SREBF2 STAT1 SUFU SUMO1 SUMO1P1 SUMO2 SUMO3 TBP TERF2 TEX11 TP53 TP73 TRIM27 TRIM5 TRIM55 TRIM63 TSG101 UBE2I UBE2L3 YWHAZ ZNF451 ZNF76
Entrez ID		7629	8554
HPRD ID		01929	16029
Ensembl ID		ENSG00000065029	ENSG00000033800
Uniprot IDs		A0A024RCU3 A0A024RCW5 P36508	O75925 Q1XBU8
PDB IDs			1V66
Enriched GO Terms of Interacting Partners?
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