VHL and COL4A2

  • Number of citations of the paper that reports this interaction (PubMedID 17700531)
  • 30
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology, far western blotting)

VHL

COL4A2

Description von Hippel-Lindau tumor suppressor collagen type IV alpha 2 chain
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Arterial stiffness ( 31070453)
  • Arterial stiffness index ( 31235810)
  • Blood urea nitrogen levels ( 31152163)
  • Coronary artery calcification ( 22144573)
  • Coronary artery disease ( 29212778 24262325 26343387)
  • Coronary artery disease (myocardial infarction, percutaneous transluminal coronary angioplasty, coronary artery bypass grafting, angina or chromic ischemic heart disease) ( 28714975)
  • Coronary heart disease ( 21378990)
  • Diastolic blood pressure ( 27841878)
  • Glomerular filtration rate ( 29403010)
  • Intake of sweets ( 31005972)
  • Ischemic stroke (small-vessel) ( 29531354)
  • LDL cholesterol ( 30275531)
  • Maximum retinal arteriolar tortuosity ( 31597446)
  • Middle temporal gyrus volume ( 31530798)
  • Myocardial infarction ( 26343387)
  • Night sleep phenotypes ( 27126917)
  • Non-lobar intracerebral hemorrhage ( 31430377)
  • Non-lobar intracerebral hemorrhage (MTAG) ( 31430377)
  • Retinal arteriolar tortuosity ( 31597446)
  • Serum bilirubin levels x sex interaction in metabolic syndrome ( 30621171)
  • Total cholesterol levels ( 30275531)
  • White matter hyperintensity burden ( 25663218)
Interacting Genes 103 interacting genes: ACTB AKT1 APP AR AURKA CAPN7 CAPZB CASR CBR1 CBX1 CBX3 CCT3 CD44 CDC34 CDKN2A CERKL CHEK2 CLU COL4A2 CSNK2A1 CUL2 CUL5 DGKI DNAJA3 DVL2 E2F1 EEF1B2 EGLN1 ELOB ELOC EPAS1 EPOR FKBP8 FLNA FN1 GHET1 H1-2 H2BC13 H4-16 HDAC1 HDAC2 HDAC3 HIF1A HIF1AN HIF3A HNRNPA2B1 HNRNPD HSPA5 HSPA8 IKBKB JADE1 KIF2C KIF3A KLF4 LANCL1 MAP1LC3B MDFI NCL NR4A1 NR4A2 NR4A3 PDCD5 PIAS4 PLD1 PLD2 POLR2G PPP5C PRDX1 PRKCI PRMT1 PRMT8 PSMC3 RB1CC1 RBPMS RBPMS2 RBX1 RHOBTB3 RNF139 RPL21 RPL5 RPS15A RWDD3 SARNP SAT2 SKP2 SLC2A1 SLC3A2 SON SP1 TPT1 TRIM28 UBE2D1 UBE2D2 UBE2I USP20 USP33 USP9X UXT VAPB VBP1 YY1AP1 ZNF197 ZNF512B 24 interacting genes: ANTXR2 ANXA7 APP ATF7IP BGN BMP3 CD93 COL4A1 CSNK2B DAZAP2 FBLN2 FN1 HABP2 MATN2 MMP9 OSM SAA1 SERPINE2 SKIL SMN1 TENT5A TGFBI TK1 VHL
Entrez ID 7428 1284
HPRD ID 01905 00355
Ensembl ID ENSG00000134086 ENSG00000134871
Uniprot IDs A0A024R2F2 A0A0S2Z4K1 P40337 A0A024RDW8 P08572
PDB IDs 1LM8 1LQB 1VCB 3ZRC 3ZRF 3ZTC 3ZTD 3ZUN 4AJY 4AWJ 4B95 4B9K 4BKS 4BKT 4W9C 4W9D 4W9E 4W9F 4W9G 4W9H 4W9I 4W9J 4W9K 4W9L 4WQO 5LLI 5N4W 5NVV 5NVW 5NVX 5NVY 5NVZ 5NW0 5NW1 5NW2 5T35 6BVB 6FMI 6FMJ 6FMK 6GFX 6GFY 6GFZ 6GMN 6GMQ 6GMR 6GMX 6HAX 6HAY 6HR2 6I7Q 6I7R 6R6H 6R7F 1LI1 5NAX 5NB2 6MPX
Enriched GO Terms of Interacting Partners?
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