VAV2 and HNRNPF

Number of citations of the paper that reports this interaction (PubMedID 18654987)
16

Data Source:
BioGRID (two hybrid)

		VAV2	HNRNPF
Description		vav guanine nucleotide exchange factor 2	heterogeneous nuclear ribonucleoprotein F
Image
GO Annotations	Cellular Component	Cytosol Plasma Membrane	Nucleus Nucleoplasm Cytosol Plasma Membrane Membrane Catalytic Step 2 Spliceosome
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Epidermal Growth Factor Receptor Binding Protein Binding Metal Ion Binding	RNA Binding Single-stranded RNA Binding Protein Binding TBP-class Protein Binding
	Biological Process	Angiogenesis Signal Transduction G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Regulation Of Cell Size Cell Migration Lamellipodium Assembly Platelet Activation Fc-epsilon Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Apoptotic Process Regulation Of GTPase Activity Positive Regulation Of Phosphatidylinositol 3-kinase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction	MRNA Splicing, Via Spliceosome RNA Processing Fibroblast Growth Factor Receptor Signaling Pathway RNA Metabolic Process Interleukin-12-mediated Signaling Pathway Regulation Of RNA Splicing
Pathways		GPVI-mediated activation cascade GPVI-mediated activation cascade NRAGE signals death through JNK Rho GTPase cycle Regulation of actin dynamics for phagocytic cup formation DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization EPH-ephrin mediated repulsion of cells G alpha (12/13) signalling events VEGFA-VEGFR2 Pathway VEGFA-VEGFR2 Pathway Signal transduction by L1 VEGFR2 mediated vascular permeability FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis	FGFR2 alternative splicing mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs			Phenethyl Isothiocyanate
Diseases
GWAS		Central corneal thickness ( 29760442) Corneal astigmatism ( 30306274) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Multiple sclerosis ( 20598377) Pre-treatment viral load in HIV-1 infection ( 31219150) vWF and FVIII levels ( 21810271)	Antisaccade task score ( 31596458)
Interacting Genes		64 interacting genes: ARIH1 BIRC6 BOD1L1 BRDT BZW1 CAV1 CBL CBLB CCNO CCT2 CCT3 CD19 CD44 CEP170 CHMP3 CRCP DCUN1D4 DNAJC21 EGFR EIF4G3 EPHB2 ERBB2 ERBB3 FNTA FUCA1 FYN GAPVD1 GRB2 HNRNPF HSPH1 IPO4 MED21 MRGBP NCKAP5 NEK3 NUP214 PHF10 PNMA1 POGZ PPM1B PRLR RAC1 RAD23A RBBP6 RHOA RHOG SERBP1 SF3A3 SH3BP2 SNW1 SOCS1 SRPK2 SRRT ST13 STK24 STOM SYK TARBP2 TCP11 TOM1L1 TTN UBE4B USP38 VCPIP1	36 interacting genes: AURKA C1orf94 CCDC33 DZIP3 EIF4ENIF1 ERG HNRNPA0 HNRNPD HNRNPH1 HNRNPH3 HNRNPM HNRNPUL1 HSFY1 HSPB1 IKZF3 NCBP1 NCBP2 NDRG1 POLR2A PRPF40A RBFOX1 RBFOX2 RBM4 SF1 SF3B4 SNRPC SUMO2 SUMO4 TFG TGM2 TLE5 TOE1 TXNL4A VAV2 YWHAQ ZNF689
Entrez ID		7410	3185
HPRD ID		02694	03023
Ensembl ID		ENSG00000160293	ENSG00000169813
Uniprot IDs		P52735	A0A024R7T3 P52597
PDB IDs		2DLZ 2DM1 2LNW 2LNX 4ROJ	2HGL 2HGM 2HGN 2KFY 2KG0 2KG1 3TFY
Enriched GO Terms of Interacting Partners?
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