VAV2 and POGZ

Number of citations of the paper that reports this interaction (PubMedID 18654987)
16

Data Source:
BioGRID (two hybrid)

		VAV2	POGZ
Description		vav guanine nucleotide exchange factor 2	pogo transposable element derived with ZNF domain
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GO Annotations	Cellular Component	Cytosol Plasma Membrane	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Phosphotyrosine Residue Binding Guanyl-nucleotide Exchange Factor Activity Epidermal Growth Factor Receptor Binding Protein Binding Metal Ion Binding	Protein Binding Metal Ion Binding
	Biological Process	Angiogenesis Signal Transduction G Protein-coupled Receptor Signaling Pathway Small GTPase Mediated Signal Transduction Regulation Of Cell Size Cell Migration Lamellipodium Assembly Platelet Activation Fc-epsilon Receptor Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Positive Regulation Of Apoptotic Process Regulation Of GTPase Activity Positive Regulation Of Phosphatidylinositol 3-kinase Activity Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Regulation Of Small GTPase Mediated Signal Transduction	Mitotic Sister Chromatid Cohesion Regulation Of Gene Expression Cell Division Kinetochore Assembly
Pathways		GPVI-mediated activation cascade GPVI-mediated activation cascade NRAGE signals death through JNK Rho GTPase cycle Regulation of actin dynamics for phagocytic cup formation DAP12 signaling FCERI mediated MAPK activation FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization EPH-ephrin mediated repulsion of cells G alpha (12/13) signalling events VEGFA-VEGFR2 Pathway VEGFA-VEGFR2 Pathway Signal transduction by L1 VEGFR2 mediated vascular permeability FCGR3A-mediated phagocytosis FCGR3A-mediated phagocytosis
Drugs
Diseases
GWAS		Central corneal thickness ( 29760442) Corneal astigmatism ( 30306274) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Multiple sclerosis ( 20598377) Pre-treatment viral load in HIV-1 infection ( 31219150) vWF and FVIII levels ( 21810271)	Blood trace element (Cu levels) ( 23720494) Body mass index ( 26426971) Pulse pressure ( 30578418)
Interacting Genes		64 interacting genes: ARIH1 BIRC6 BOD1L1 BRDT BZW1 CAV1 CBL CBLB CCNO CCT2 CCT3 CD19 CD44 CEP170 CHMP3 CRCP DCUN1D4 DNAJC21 EGFR EIF4G3 EPHB2 ERBB2 ERBB3 FNTA FUCA1 FYN GAPVD1 GRB2 HNRNPF HSPH1 IPO4 MED21 MRGBP NCKAP5 NEK3 NUP214 PHF10 PNMA1 POGZ PPM1B PRLR RAC1 RAD23A RBBP6 RHOA RHOG SERBP1 SF3A3 SH3BP2 SNW1 SOCS1 SRPK2 SRRT ST13 STK24 STOM SYK TARBP2 TCP11 TOM1L1 TTN UBE4B USP38 VCPIP1	22 interacting genes: APP BANP CDK6 CREB1 DAB1 DAZAP2 GABPB1 H3-4 HGS NFYA NFYC NRF1 POU2F1 PRR20A QRICH1 RBPMS SP1 SUMO2 UBAP2L VAV2 ZBTB24 ZXDC
Entrez ID		7410	23126
HPRD ID		02694	11445
Ensembl ID		ENSG00000160293	ENSG00000143442
Uniprot IDs		P52735	Q7Z3K3
PDB IDs		2DLZ 2DM1 2LNW 2LNX 4ROJ	2E72 2N3A 6EMP
Enriched GO Terms of Interacting Partners?
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