UQCRB and MAGEA4

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology)
HPRD (two hybrid)

		UQCRB	MAGEA4
Description		ubiquinol-cytochrome c reductase binding protein	MAGE family member A4
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GO Annotations	Cellular Component	Mitochondrial Inner Membrane Mitochondrial Respiratory Chain Mitochondrial Respiratory Chain Complex III	Cellular_component
	Molecular Function	Protein Binding	Molecular_function Protein Binding
	Biological Process	Oxidative Phosphorylation Mitochondrial Electron Transport, Ubiquinol To Cytochrome C Aerobic Respiration Mitochondrial Respiratory Chain Complex III Assembly Oxidation-reduction Process	Biological_process
Pathways		Respiratory electron transport
Drugs		2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol 5-n-undecyl-6-hydroxy-4,7-dioxobenzothiazole METHYL (2Z)-2-(2-{[6-(2-CYANOPHENOXY)PYRIMIDIN-4-YL]OXY}PHENYL)-3-METHOXYACRYLATE 5-HEPTYL-6-HYDROXY-1,3-BENZOTHIAZOLE-4,7-DIONE (5S)-3-ANILINO-5-(2,4-DIFLUOROPHENYL)-5-METHYL-1,3-OXAZOLIDINE-2,4-DIONE FAMOXADONE METHYL (2Z)-3-METHOXY-2-{2-[(E)-2-PHENYLVINYL]PHENYL}ACRYLATE 2-NONYL-4-HYDROXYQUINOLINE N-OXIDE UBIQUINONE-2
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Huntington's disease progression ( 28642124)
Interacting Genes		5 interacting genes: ACCS HSPB1 LRRK2 MAGEA1 MAGEA4	17 interacting genes: AMOT AMOTL2 APP ARNT2 BEX2 GTF3C1 HLA-A POT1 PSMD10 RAD18 TEKT4 TIGD5 TK1 TRIM69 UBXN6 UQCRB WBP2
Entrez ID		7381	4103
HPRD ID		11770	02167
Ensembl ID		ENSG00000156467	ENSG00000147381
Uniprot IDs		P14927	A0A024RC12 P43358
PDB IDs		5XTE 5XTH 5XTI	1I4F 2WA0
Enriched GO Terms of Interacting Partners?
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