UBE2D2 and WRN

  • Number of citations of the paper that reports this interaction (PubMedID 30532073)
  • 2
  • Data Source:
  • BioGRID (enzymatic study)

UBE2D2

WRN

Description ubiquitin conjugating enzyme E2 D2 WRN RecQ like helicase
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GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 30820047)
  • Body mass index ( 26426971)
  • Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
  • Chronotype ( 30696823)
  • Cough in response to angiotensin-converting enzyme inhibitor drugs ( 28084903)
  • Daytime sleep phenotypes ( 27126917)
  • Exercise treadmill test traits ( 17903301)
  • Fasting glucose change (long-term) ( 31263163)
  • Intelligence (MTAG) ( 29326435)
  • Lifespan ( 25918517)
  • Logical memory (delayed recall) in mild cognitive impairment ( 29274321)
  • Logical memory (immediate recall) in mild cognitive impairment ( 29274321)
  • Metabolite levels ( 23823483)
  • Morning person ( 30696823)
Interacting Genes 234 interacting genes: AMFR ANAPC11 ANAPC2 AREL1 ARIH2 BARD1 BFAR BIRC2 BIRC3 BIRC7 BIRC8 BMI1 BRAP BRCA1 BTRC CADPS2 CBL CBLB CBLC CCNB1 CDKN1B CHFR CNOT4 COP1 CUL3 DCAF1 DDX58 DTX1 DTX3 DTX3L DZIP3 EPS15 F12 FBXL3 FBXO2 FBXO4 FBXO7 FBXW2 HACE1 HECTD1 HECTD3 HECTD4 HECW1 HECW2 HERC1 HERC2 HERC4 HERC5 HUWE1 ITCH KAT2B KCMF1 LNX1 LNX2 LRSAM1 LTN1 MAP3K1 MAPT MARCHF3 MARCHF5 MARCHF6 MARCHF7 MDM2 MDM4 MEX3A MEX3C MGRN1 MIB1 MIB2 MID1 MKRN3 MUL1 MYCBP2 MYLIP NAT10 NBR1 NEDD4 NEDD4L NFKBIA NPR1 NSMCE1 OTUB1 PDZRN3 PELI1 PER2 PHRF1 PJA1 PJA2 POLL POLM PRKN QSOX1 RAD18 RAF1 RAG1 RBCK1 RBX1 RC3H1 RC3H2 RCHY1 RELA RFFL RFWD3 RING1 RLIM RMND5B RNF10 RNF103 RNF11 RNF111 RNF114 RNF115 RNF122 RNF123 RNF125 RNF126 RNF13 RNF130 RNF135 RNF138 RNF14 RNF146 RNF150 RNF151 RNF166 RNF167 RNF168 RNF170 RNF181 RNF185 RNF186 RNF19A RNF19B RNF2 RNF20 RNF213 RNF216 RNF220 RNF224 RNF25 RNF26 RNF31 RNF34 RNF38 RNF4 RNF40 RNF43 RNF5 RNF7 RSPRY1 RTF2 SIAH1 SIAH2 SMURF1 SMURF2 SOCS6 SPOP SQSTM1 STAM2 STK11 STUB1 SYVN1 TOPORS TRAF2 TRAF6 TRAF7 TRAIP TRIM10 TRIM13 TRIM17 TRIM2 TRIM21 TRIM23 TRIM25 TRIM26 TRIM27 TRIM28 TRIM3 TRIM31 TRIM32 TRIM33 TRIM35 TRIM36 TRIM37 TRIM38 TRIM39 TRIM41 TRIM43 TRIM45 TRIM46 TRIM47 TRIM5 TRIM50 TRIM54 TRIM55 TRIM62 TRIM63 TRIM65 TRIM7 TRIM8 TRIP12 TTC3 UBA1 UBA3 UBA5 UBA6 UBASH3B UBB UBC UBD UBE3A UBE3C UBE4A UBE4B UBOX5 UBR1 UBR2 UBR3 UBR4 UBR5 UFM1 UHRF2 UVSSA VHL VPS11 VPS18 WRN WSB1 WWP1 WWP2 XIAP ZNRF1 ZNRF2 ZNRF4 34 interacting genes: ATM ATRX BARD1 BLM BRCA1 CDKN2A FEN1 H2AX MDC1 MDM2 PARP1 PCNA POLB POLD2 POLK POLR1C PRKAR1B PRKDC RAD1 RAD51 RAD52 RAD54B RAD9A RPA1 SUMO1 SUMO2 TERF2 TP53 UBE2D2 UBXN8 VCP WRNIP1 XRCC5 XRCC6
Entrez ID 7322 7486
HPRD ID 04268 05212
Ensembl ID ENSG00000131508 ENSG00000165392
Uniprot IDs P62837 Q14191
PDB IDs 1UR6 1W4U 2CLW 2ESK 2ESO 2ESP 2ESQ 3A33 3JVZ 3JW0 3L1Y 3TGD 3ZNI 4A49 4A4B 4A4C 4AUQ 4DDG 4DDI 4LDT 4V3K 4V3L 4WZ3 5D0K 5D0M 5D1K 5D1L 5D1M 5EDV 5MNJ 5ULF 5ULH 5ULK 5VZW 5ZBU 6HPR 2AXL 2DGZ 2E1E 2E1F 2FBT 2FBV 2FBX 2FBY 2FC0 3AAF
Enriched GO Terms of Interacting Partners?
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