UBE2D2 and HECTD4

  • Number of citations of the paper that reports this interaction (PubMedID 29643511)
  • 14

UBE2D2

HECTD4

Description ubiquitin conjugating enzyme E2 D2 HECT domain E3 ubiquitin protein ligase 4
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease (late onset) ( 30820047)
  • Body mass index ( 26426971)
  • Immune reponse to smallpox (secreted IFN-alpha) ( 22610502)
  • Alcohol consumption (max-drinks) ( 29460428)
  • Alcohol dependence symptom count ( 29460428)
  • Body mass index ( 26426971 28892062)
  • Celiac disease and Rheumatoid arthritis ( 26546613)
  • Coffee consumption ( 29367735)
  • Diastolic blood pressure ( 27736895)
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962)
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Granulocyte count ( 27863252)
  • HDL cholesterol levels ( 28334899)
  • High density lipoprotein cholesterol levels ( 30718733)
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Metabolic syndrome ( 30382898)
  • Myeloid white cell count ( 27863252)
  • Neutrophil count ( 27863252)
  • Reaction time ( 29844566)
  • Response to alcohol consumption (flushing response) ( 29460428)
  • Serum uric acid levels ( 29124443)
  • Sum basophil neutrophil counts ( 27863252)
  • Sum neutrophil eosinophil counts ( 27863252)
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
  • Thoracic-to-hip circumference ratio ( 26675016)
  • Urate levels ( 31578528)
  • White blood cell count ( 27863252)
Interacting Genes 234 interacting genes: AMFR ANAPC11 ANAPC2 AREL1 ARIH2 BARD1 BFAR BIRC2 BIRC3 BIRC7 BIRC8 BMI1 BRAP BRCA1 BTRC CADPS2 CBL CBLB CBLC CCNB1 CDKN1B CHFR CNOT4 COP1 CUL3 DCAF1 DDX58 DTX1 DTX3 DTX3L DZIP3 EPS15 F12 FBXL3 FBXO2 FBXO4 FBXO7 FBXW2 HACE1 HECTD1 HECTD3 HECTD4 HECW1 HECW2 HERC1 HERC2 HERC4 HERC5 HUWE1 ITCH KAT2B KCMF1 LNX1 LNX2 LRSAM1 LTN1 MAP3K1 MAPT MARCHF3 MARCHF5 MARCHF6 MARCHF7 MDM2 MDM4 MEX3A MEX3C MGRN1 MIB1 MIB2 MID1 MKRN3 MUL1 MYCBP2 MYLIP NAT10 NBR1 NEDD4 NEDD4L NFKBIA NPR1 NSMCE1 OTUB1 PDZRN3 PELI1 PER2 PHRF1 PJA1 PJA2 POLL POLM PRKN QSOX1 RAD18 RAF1 RAG1 RBCK1 RBX1 RC3H1 RC3H2 RCHY1 RELA RFFL RFWD3 RING1 RLIM RMND5B RNF10 RNF103 RNF11 RNF111 RNF114 RNF115 RNF122 RNF123 RNF125 RNF126 RNF13 RNF130 RNF135 RNF138 RNF14 RNF146 RNF150 RNF151 RNF166 RNF167 RNF168 RNF170 RNF181 RNF185 RNF186 RNF19A RNF19B RNF2 RNF20 RNF213 RNF216 RNF220 RNF224 RNF25 RNF26 RNF31 RNF34 RNF38 RNF4 RNF40 RNF43 RNF5 RNF7 RSPRY1 RTF2 SIAH1 SIAH2 SMURF1 SMURF2 SOCS6 SPOP SQSTM1 STAM2 STK11 STUB1 SYVN1 TOPORS TRAF2 TRAF6 TRAF7 TRAIP TRIM10 TRIM13 TRIM17 TRIM2 TRIM21 TRIM23 TRIM25 TRIM26 TRIM27 TRIM28 TRIM3 TRIM31 TRIM32 TRIM33 TRIM35 TRIM36 TRIM37 TRIM38 TRIM39 TRIM41 TRIM43 TRIM45 TRIM46 TRIM47 TRIM5 TRIM50 TRIM54 TRIM55 TRIM62 TRIM63 TRIM65 TRIM7 TRIM8 TRIP12 TTC3 UBA1 UBA3 UBA5 UBA6 UBASH3B UBB UBC UBD UBE3A UBE3C UBE4A UBE4B UBOX5 UBR1 UBR2 UBR3 UBR4 UBR5 UFM1 UHRF2 UVSSA VHL VPS11 VPS18 WRN WSB1 WWP1 WWP2 XIAP ZNRF1 ZNRF2 ZNRF4 2 interacting genes: UBE2D2 UBE2L3
Entrez ID 7322 283450
HPRD ID 04268 08170
Ensembl ID ENSG00000131508 ENSG00000173064
Uniprot IDs P62837 F8VWT9
PDB IDs 1UR6 1W4U 2CLW 2ESK 2ESO 2ESP 2ESQ 3A33 3JVZ 3JW0 3L1Y 3TGD 3ZNI 4A49 4A4B 4A4C 4AUQ 4DDG 4DDI 4LDT 4V3K 4V3L 4WZ3 5D0K 5D0M 5D1K 5D1L 5D1M 5EDV 5MNJ 5ULF 5ULH 5ULK 5VZW 5ZBU 6HPR
Enriched GO Terms of Interacting Partners?
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