TTC1 and GNA15

Number of citations of the paper that reports this interaction (PubMedID 12748287)
15

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		TTC1	GNA15
Description		tetratricopeptide repeat domain 1	G protein subunit alpha 15
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Peroxisomal Membrane Cytosol	Cell Heterotrimeric G-protein Complex Plasma Membrane Synapse
	Molecular Function	Protein Binding Unfolded Protein Binding	G Protein-coupled Receptor Binding GTPase Activity GTP Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding
	Biological Process	Protein Folding	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Platelet Activation Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Phospholipase C-activating Dopamine Receptor Signaling Pathway
Pathways			Acetylcholine regulates insulin secretion Acetylcholine regulates insulin secretion G alpha (q) signalling events G alpha (q) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 Thromboxane signalling through TP receptor Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Thrombin signalling through proteinase activated receptors (PARs)
Drugs
Diseases
GWAS		Diastolic blood pressure ( 27841878) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Glucose homeostasis traits ( 25524916) Heart failure ( 20445134)
Interacting Genes		17 interacting genes: ACY1 CRY2 GNA15 GNAI2 GNAQ GNAS HRAS HSPA1A HSPA4 HSPA8 NDE1 PSTPIP1 SH3BP4 SOX5 SPP1 SREBF2 TGFBR1	19 interacting genes: ADRB2 APP CHRM2 CNR1 CNR2 CXCR1 CXCR2 F2R GRK2 GRM2 GRM4 HRH4 LTB4R OPRD1 OPRK1 OPRM1 PRKCA RGS2 TTC1
Entrez ID		7265	2769
HPRD ID		11881	00760
Ensembl ID		ENSG00000113312	ENSG00000060558
Uniprot IDs		Q99614	P30679
PDB IDs
Enriched GO Terms of Interacting Partners?
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