GNA15 and TTC1

Number of citations of the paper that reports this interaction (PubMedID 12748287)
15

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		GNA15	TTC1
Description		G protein subunit alpha 15	tetratricopeptide repeat domain 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Heterotrimeric G-protein Complex Plasma Membrane Synapse	Peroxisomal Membrane Cytosol
	Molecular Function	G Protein-coupled Receptor Binding GTPase Activity GTP Binding G-protein Beta/gamma-subunit Complex Binding Metal Ion Binding	Protein Binding Unfolded Protein Binding
	Biological Process	G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Activation Of Phospholipase C Activity Phospholipase C-activating G Protein-coupled Acetylcholine Receptor Signaling Pathway Platelet Activation Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G Protein-coupled Signaling Pathway Phospholipase C-activating Dopamine Receptor Signaling Pathway	Protein Folding
Pathways		Acetylcholine regulates insulin secretion Acetylcholine regulates insulin secretion G alpha (q) signalling events G alpha (q) signalling events ADP signalling through P2Y purinoceptor 1 ADP signalling through P2Y purinoceptor 1 Thromboxane signalling through TP receptor Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion Thrombin signalling through proteinase activated receptors (PARs)
Drugs
Diseases
GWAS		Glucose homeostasis traits ( 25524916) Heart failure ( 20445134)	Diastolic blood pressure ( 27841878) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		19 interacting genes: ADRB2 APP CHRM2 CNR1 CNR2 CXCR1 CXCR2 F2R GRK2 GRM2 GRM4 HRH4 LTB4R OPRD1 OPRK1 OPRM1 PRKCA RGS2 TTC1	17 interacting genes: ACY1 CRY2 GNA15 GNAI2 GNAQ GNAS HRAS HSPA1A HSPA4 HSPA8 NDE1 PSTPIP1 SH3BP4 SOX5 SPP1 SREBF2 TGFBR1
Entrez ID		2769	7265
HPRD ID		00760	11881
Ensembl ID		ENSG00000060558	ENSG00000113312
Uniprot IDs		P30679	Q99614
PDB IDs
Enriched GO Terms of Interacting Partners?
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