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C1QBP and HMGB2
Number of citations of the paper that reports this interaction (PubMedID
29721183
)
2
Data Source:
BioGRID
(two hybrid)
C1QBP
HMGB2
Description
complement C1q binding protein
high mobility group box 2
Image
No pdb structure
GO Annotations
Cellular Component
Extracellular Space
Nucleus
Nucleolus
Cytoplasm
Mitochondrion
Mitochondrial Matrix
Cytosol
Plasma Membrane
Cell Surface
Membrane
Presynaptic Active Zone
Glutamatergic Synapse
GABA-ergic Synapse
Nuclear Chromatin
Condensed Chromosome
Extracellular Space
Cell
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Protein-containing Complex
Perinuclear Region Of Cytoplasm
Molecular Function
Complement Component C1q Binding
Transcription Corepressor Activity
MRNA Binding
Protein Kinase C Binding
Protein Binding
Hyaluronic Acid Binding
Transcription Factor Binding
Translation Activator Activity
Kininogen Binding
Adrenergic Receptor Binding
Mitochondrial Ribosome Binding
Four-way Junction DNA Binding
Proximal Promoter Sequence-specific DNA Binding
DNA Binding
Damaged DNA Binding
Double-stranded DNA Binding
Single-stranded DNA Binding
Transcription Coactivator Activity
RNA Binding
Protein Binding
Transcription Factor Binding
Drug Binding
DNA Binding, Bending
Protein Domain Specific Binding
Chemoattractant Activity
Transcription Regulatory Region DNA Binding
Non-sequence-specific DNA Binding, Bending
RAGE Receptor Binding
Supercoiled DNA Binding
Biological Process
Negative Regulation Of Transcription By RNA Polymerase II
MRNA Processing
Apoptotic Process
Immune Response
Complement Activation, Classical Pathway
Blood Coagulation, Intrinsic Pathway
RNA Splicing
Phosphatidylinositol 3-kinase Signaling
Viral Process
Regulation Of Complement Activation
Negative Regulation Of Interferon-gamma Production
Negative Regulation Of Interleukin-12 Production
Negative Regulation Of MDA-5 Signaling Pathway
Negative Regulation Of RIG-I Signaling Pathway
Mature Ribosome Assembly
Positive Regulation Of Apoptotic Process
Innate Immune Response
Positive Regulation Of Cell Adhesion
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of Defense Response To Virus
Positive Regulation Of Protein Kinase B Signaling
Positive Regulation Of Mitochondrial Translation
Positive Regulation Of Neutrophil Chemotaxis
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Positive Regulation Of Trophoblast Cell Migration
Positive Regulation Of Dendritic Cell Chemotaxis
Positive Regulation Of Endothelial Cell Proliferation
Inflammatory Response To Antigenic Stimulus
DNA Topological Change
Apoptotic DNA Fragmentation
DNA Recombination
Chromatin Organization
Nucleosome Assembly
Chromatin Remodeling
Regulation Of Transcription, DNA-templated
Regulation Of Transcription By RNA Polymerase II
Spermatid Nucleus Differentiation
Male Gonad Development
Positive Regulation Of Nuclease Activity
DNA Geometric Change
Response To Lipopolysaccharide
Positive Regulation Of Interferon-beta Production
V(D)J Recombination
Response To Drug
Positive Regulation Of DNA Binding
Innate Immune Response
Positive Regulation Of Innate Immune Response
Positive Regulation Of Erythrocyte Differentiation
Positive Regulation Of Megakaryocyte Differentiation
Negative Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription, DNA-templated
Positive Regulation Of Transcription By RNA Polymerase II
Response To Steroid Hormone
Regulation Of Neurogenesis
Defense Response To Gram-negative Bacterium
Defense Response To Gram-positive Bacterium
Positive Chemotaxis
DNA Ligation Involved In DNA Repair
Cell Chemotaxis
Cellular Response To Lipopolysaccharide
Regulation Of Stem Cell Proliferation
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Apoptotic factor-mediated response
Intrinsic Pathway of Fibrin Clot Formation
Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function
Apoptosis induced DNA fragmentation
Drugs
Hyaluronic acid
Copper
Diseases
GWAS
Rheumatoid arthritis (
30423114
24390342
)
Interacting Genes
26 interacting genes:
C1QA
CEBPA
COIL
EXOSC6
GAB1
GABRB1
HABP4
HMGB1
HMGB2
HNRNPD
HRK
MAPK1
MAPK3
MMP14
NFKBIE
NFYB
PRKCA
PRKCD
PRKCZ
PRKD1
PRRC2A
SRSF1
SRSF9
TOP3B
YWHAB
YWHAG
37 interacting genes:
APEX1
APP
AR
ARCN1
C1QBP
CACTIN
CHAF1A
CREBBP
CSNK1A1
EIF1
FBXO7
GZMA
GZMK
H3-3A
HACD3
HDLBP
HMGA1
LZTS1
MIEN1
NAP1L1
NCBP3
NEXN
NR3C1
PGR
PKNOX1
POU2F1
POU2F2
POU3F1
POU5F1
PRKDC
RAG1
SAMM50
SET
TP53
ZNF428
ZNF622
ZNF668
Entrez ID
708
3148
HPRD ID
03168
01229
Ensembl ID
ENSG00000108561
ENSG00000164104
Uniprot IDs
Q07021
P26583
PDB IDs
1P32
3RPX
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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