TFAP2A and CASP6

  • Number of citations of the paper that reports this interaction (PubMedID 11438643)
  • 14
  • Data Source:
  • HPRD (in vitro, in vivo)

TFAP2A

CASP6

Description transcription factor AP-2 alpha caspase 6
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Breast cancer in BRCA2 mutation carriers ( 23544012)
  • Glucose homeostasis traits ( 25524916)
  • Iron status biomarkers (ferritin levels) ( 28334935)
  • Metabolite levels ( 23823483)
  • Ovarian cancer ( 30557369)
  • Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261)
  • Zinc levels ( 26025379)
  • Risk-taking tendency (4-domain principal component model) ( 30643258)
Interacting Genes 37 interacting genes: APC CASP1 CASP3 CASP6 CITED2 CITED4 CLTC CSNK2A1 CSNK2B CTNNB1 DEK EP300 EPN1 EPN2 EPS15 GSTO2 HIP1 KCTD15 LDLRAP1 MAGI1 MKRN3 MYC NFKB1 NPM1 PPARG PRKAA2 PRKD1 RB1 SRA1 SUMO4 SYT1 TP53 UBE2I VEGFA WWP1 WWP2 YBX1 38 interacting genes: APP CASP10 CASP3 CASP8 CFLAR CHD3 COPS6 DSP EIF2S1 HTT IKBKG KRT18 LMNA LMNB1 MAPK6 MAPT NEDD4 NUAK1 PCYT1A PIN1 PPL PRKAB2 PRKCZ PSEN1 PSEN2 PSME3 RB1 SATB1 SP1 SRF SRP72 TAB1 TFAP2A TOP1 TRAF1 UBE4A UBE4B VIM
Entrez ID 7020 839
HPRD ID 00128 03321
Ensembl ID ENSG00000137203 ENSG00000138794
Uniprot IDs P05549 P55212
PDB IDs 1MI9 2WDP 3K7E 3NKF 3NR2 3OD5 3P45 3P4U 3QNW 3S70 3S8E 3V6L 3V6M 4EJF 4FXO 4HVA 4IYR 4N5D 4N6G 4N7J 4N7M 4NBK 4NBL 4NBN 6DEU 6DEV
Enriched GO Terms of Interacting Partners?
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