TBX15 and VENTX

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TBX15	VENTX
Description		T-box transcription factor 15	VENT homeobox
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Nuclear Chromatin Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific RNA Polymerase II Activating Transcription Factor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Protein Homodimerization Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Cell Fate Specification Positive Regulation Of Transcription By RNA Polymerase II Embryonic Cranial Skeleton Morphogenesis	Regulation Of Transcription By RNA Polymerase II Multicellular Organism Development Positive Regulation Of Transcription By RNA Polymerase II
Pathways			Senescence-Associated Secretory Phenotype (SASP) Transcriptional Regulation by VENTX
Drugs
Diseases		Cousin syndrome
GWAS		Antitragus size ( 26105758) Birth weight ( 31043758) Body mass index ( 28892062 25673413) Breast size ( 27182965) Chin dimples ( 27182965) Congenital heart malformation ( 23708190) Ear morphology ( 26105758) Excessive hairiness ( 29895819) Facial morphology ( 31763980) Facial morphology traits (63 three-dimensional facial segments) ( 29459680) Folding of antihelix ( 26105758) Heel bone mineral density ( 30598549 28869591) Height ( 31562340) Lung function (FVC) ( 28166213) Lung function (low FEV1 vs high FEV1) ( 26423011) Male-pattern baldness ( 27182965 28196072) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 25673412 28448500) Waist-hip ratio ( 25673412 20935629) Waist-to-hip ratio adjusted for BMI ( 28552196) Waist-to-hip ratio adjusted for BMI (additive genetic model) ( 30778226) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in inactive individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 26785701 25673412 28448500)
Interacting Genes		3 interacting genes: ATXN1 POLE2 VENTX	9 interacting genes: C1orf94 DAB1 IRF9 KRTAP12-2 KRTAP12-4 RBPMS TBX15 TBX22 TLE2
Entrez ID		6913	27287
HPRD ID		16035	06197
Ensembl ID		ENSG00000092607	ENSG00000151650
Uniprot IDs		Q8N8P2 Q96SF7	O95231
PDB IDs
Enriched GO Terms of Interacting Partners?
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