TBL1X and CORO2A

Number of citations of the paper that reports this interaction (PubMedID 12628926)
174

Data Source:
HPRD (in vitro)

		TBL1X	CORO2A
Description		transducin beta like 1 X-linked	coronin 2A
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nucleus Nucleoplasm Transcriptional Repressor Complex Mitotic Spindle	Transcriptional Repressor Complex
	Molecular Function	Transcription Corepressor Activity Protein Binding Beta-catenin Binding Protein C-terminus Binding Transcription Factor Binding Protein Domain Specific Binding Histone Binding Transcription Regulatory Region DNA Binding	Protein Binding Actin Filament Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Proteolysis Sensory Perception Of Sound Histone Deacetylation Regulation Of Lipid Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Protein Stabilization Positive Regulation Of Canonical Wnt Signaling Pathway	Intracellular Signal Transduction
Pathways		RORA activates gene expression BMAL1:CLOCK,NPAS2 activates circadian gene expression PPARA activates gene expression PPARA activates gene expression NOTCH1 Intracellular Domain Regulates Transcription Transcriptional activation of mitochondrial biogenesis Activation of gene expression by SREBF (SREBP) Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants HDACs deacetylate histones Notch-HLH transcription pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by PPARalpha Circadian Clock Loss of MECP2 binding ability to the NCoR/SMRT complex Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux HCMV Early Events
Drugs
Diseases
GWAS		Prostate cancer ( 23535732)	Peginterferon alfa-2a treatment response in chronic hepatitis B infection ( 30972912) Pulse pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		28 interacting genes: CDC34 CORO2A CTNNB1 DLX3 DNAJB4 FOXK2 GPS2 H2AC18 H2BC21 H3C14 H4C1 H4C14 HDAC3 HP HR KHDRBS1 MECP2 NCOR1 NCOR2 SKP1 TAB2 TBL1XR1 TERF1 THRA THRB TINF2 UBE2D1 UBE2I	4 interacting genes: HDAC3 TBL1X TBL1XR1 UBE2I
Entrez ID		6907	7464
HPRD ID		02183	03695
Ensembl ID		ENSG00000101849	ENSG00000106789
Uniprot IDs		A0A024RBV9 O60907	A0A024R150 A8K9S3 Q92828
PDB IDs		2XTC 2XTD 2XTE
Enriched GO Terms of Interacting Partners?
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