MAP3K7 and PINK1

  • Number of citations of the paper that reports this interaction (PubMedID 22643835)
  • 7
  • Data Source:
  • BioGRID (enzymatic study)

MAP3K7

PINK1

Description mitogen-activated protein kinase kinase kinase 7 PTEN induced kinase 1
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (sporadic) ( 24529757)
  • Asthma ( 29273806)
  • Asthma (adult onset) ( 31036433)
  • Asthma (childhood onset) ( 31036433)
  • Bone mineral density (hip) ( 30172743)
  • Celiac disease ( 20190752)
  • Graves' disease ( 21841780)
  • Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)
  • Response to inhaled corticosteroid treatment in asthma (change in FEV1) ( 24792382)
  • Severity of nausea and vomiting of pregnancy ( 29563502)
  • Household income (MTAG) ( 31844048)
  • Itch intensity from mosquito bite adjusted by bite size ( 28199695)
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
Interacting Genes 65 interacting genes: BBS10 BCL10 CARD11 CHUK COPS5 CYLD EIF2AK2 ELP1 EZH2 FOS GPR25 HGS HIPK2 IKBKB IKBKG IL17RD IRAK1 MAP2K4 MAP2K6 MAP3K14 MAP3K3 MAP3K5 MAP4K1 MAP4K4 MAPK14 MAPK6 MAPK8 MAPK8IP1 MAVS MUL1 NAIP NDUFS6 NFKBIA NOD2 NRIP1 PEBP1 PELI3 PINK1 PPM1B PPM1L PPP2R1A PPP5C PRKAB1 RBX1 RELA RNF19A ROR2 SMAD3 SMAD6 SMAD7 STAT3 STRADB TAB1 TAB2 TGFBR1 TNFRSF11A TRAF3 TRAF3IP2 TRAF6 UBASH3A UBC VRK2 XIAP ZNF593 ZNF746 18 interacting genes: APPL2 BAG2 BAG5 CRLS1 DNM1L FBXO7 HSD17B10 HSH2D MAP3K7 MARK2 PARK7 PRKACA SNCAIP STAT3 TGM2 TRAF6 UBC UBE2M
Entrez ID 6885 65018
HPRD ID 04011 10514
Ensembl ID ENSG00000135341 ENSG00000158828
Uniprot IDs O43318 Q9BXM7
PDB IDs 2EVA 2YIY 4GS6 4L3P 4L52 4L53 4O91 5E7R 5GJD 5GJF 5GJG 5J7S 5J8I 5J9L 5JGA 5JGB 5JGD 5JH6 5JK3 5V5N
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?