TAF5 and CPSF1

Number of citations of the paper that reports this interaction (PubMedID 9311784)
120

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		TAF5	CPSF1
Description		TATA-box binding protein associated factor 5	cleavage and polyadenylation specific factor 1
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor TFIID Complex Nucleolus Actin Cytoskeleton Transcription Factor TFTC Complex	Nucleus Nucleoplasm MRNA Cleavage And Polyadenylation Specificity Factor Complex
	Molecular Function	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Identical Protein Binding Transcription Regulatory Region DNA Binding	Protein Binding Enzyme Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Viral Process SnRNA Transcription By RNA Polymerase II Regulation Of Signal Transduction By P53 Class Mediator	MRNA Splicing, Via Spliceosome Termination Of RNA Polymerase II Transcription MRNA Polyadenylation TRNA Splicing, Via Endonucleolytic Cleavage And Ligation MRNA Export From Nucleus MRNA 3'-end Processing Pre-mRNA Cleavage Required For Polyadenylation
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	Transport of Mature mRNA Derived from an Intronless Transcript tRNA processing in the nucleus mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Processing of Intronless Pre-mRNAs
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Height ( 31562340) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 25056061 23974872)	Educational attainment ( 25201988)
Interacting Genes		16 interacting genes: CPSF1 GTF2F2 H3-4 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	16 interacting genes: CSTF2T CSTF3 GLIS2 HMOX1 IL7R MCM2 NEDD4 PAPOLA POLR2A PRRC2A REL TAF11 TAF12 TAF13 TAF5 TAF7
Entrez ID		6877	29894
HPRD ID		11876	05823
Ensembl ID		ENSG00000148835	ENSG00000071894
Uniprot IDs		Q15542	Q10570
PDB IDs		2NXP 6F3T 6MZC 6MZD 6MZL 6MZM	6BLY 6BM0 6DNH 6F9N 6FBS 6FUW 6URG 6URO
Enriched GO Terms of Interacting Partners?
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