TACC1 and STX5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		TACC1	STX5
Description		transforming acidic coiled-coil containing protein 1	syntaxin 5
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Microtubule Organizing Center Cytosol Membrane Midbody	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane
	Molecular Function	Protein Binding Nuclear Receptor Binding Estrogen Receptor Binding Glucocorticoid Receptor Binding Retinoic Acid Receptor Binding Peroxisome Proliferator Activated Receptor Binding Retinoid X Receptor Binding Thyroid Hormone Receptor Binding	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding Protein N-terminus Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Spindle Organization Cell Proliferation Cerebral Cortex Development Cell Division Positive Regulation Of Nuclear Receptor Transcription Coactivator Activity	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization
Pathways			COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Chronic mountain sickness ( 31417607) Midgestational circulating levels of PBDEs ( 28235828)	Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		15 interacting genes: AURKA AURKB BTRC HTT ITSN2 KAT2A KDM1A LSM7 MEMO1 SH2D4A SNRPG STX5 TDRD7 THAP12 YEATS4	29 interacting genes: APLP1 BAG6 BET1 COPS6 GET3 GOSR1 GOSR2 HAP1 IMMT KASH5 LMNA LNX1 LRIF1 MAGEA6 NAPA NAPB NSFL1C SCFD1 SEC22B SNAP23 SNAP25 STX4 STXBP1 TACC1 TP53 USO1 VAPB VCP VCPIP1
Entrez ID		6867	6811
HPRD ID		10391	04426
Ensembl ID		ENSG00000147526	ENSG00000162236
Uniprot IDs		E7EVI4 O75410 Q5HYH0	B4DKR0 Q13190
PDB IDs			3EFO
Enriched GO Terms of Interacting Partners?
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