STX5 and STXBP1

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		STX5	STXBP1
Description		syntaxin 5	syntaxin binding protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Endomembrane System ER To Golgi Transport Vesicle Membrane Integral Component Of Membrane SNARE Complex Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane	Nucleoplasm Cytoplasm Mitochondrion Cytosol Cytoskeleton Plasma Membrane Axon Platelet Alpha Granule Protein-containing Complex Phagocytic Vesicle Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Extracellular Exosome Postsynapse Glutamatergic Synapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Cadherin Binding Protein N-terminus Binding	SNARE Binding RNA Binding Protein Binding Syntaxin-1 Binding Protein Kinase Binding Protein Domain Specific Binding Syntaxin Binding Identical Protein Binding Phospholipase Binding Protein N-terminus Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Vesicle Fusion Early Endosome To Golgi Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of Protein Catabolic Process COPII Vesicle Coating Vesicle Docking Vesicle Fusion With Golgi Apparatus Golgi Disassembly Regulation Of Golgi Organization	Platelet Degranulation Developmental Process Involved In Reproduction Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axon Target Recognition Regulation Of Synaptic Vesicle Priming Glutamate Secretion Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Maturation Negative Regulation Of Protein Complex Assembly Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of Synaptic Transmission, GABAergic Response To Estradiol SNARE Complex Assembly Regulation Of SNARE Complex Assembly Positive Regulation Of Mast Cell Degranulation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Calcium Ion-dependent Exocytosis Protein Stabilization Long-term Synaptic Depression Platelet Aggregation Cellular Response To Interferon-gamma Protein Localization To Plasma Membrane Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Vesicle Docking Positive Regulation Of Glutamate Secretion, Neurotransmission Regulation Of Acrosomal Vesicle Exocytosis
Pathways		COPII-mediated vesicle transport Cargo concentration in the ER COPI-mediated anterograde transport Intra-Golgi traffic Insertion of tail-anchored proteins into the endoplasmic reticulum membrane Insertion of tail-anchored proteins into the endoplasmic reticulum membrane	Regulation of insulin secretion Neurexins and neuroligins
Drugs
Diseases			Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS		Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Whole brain grey matter density ( 31530798)
Interacting Genes		29 interacting genes: APLP1 BAG6 BET1 COPS6 GET3 GOSR1 GOSR2 HAP1 IMMT KASH5 LMNA LNX1 LRIF1 MAGEA6 NAPA NAPB NSFL1C SCFD1 SEC22B SNAP23 SNAP25 STX4 STXBP1 TACC1 TP53 USO1 VAPB VCP VCPIP1	31 interacting genes: APBA1 APBA2 APP C19orf57 CDK5 CDK5R1 DOC2A DOC2B HGS MAPT MEOX2 MTDH MTNR1A NEFH NEFM PLD1 PLD2 PRKCA PRKCB PRKCG SPTBN1 SQSTM1 STOM STX1A STX1B STX2 STX3 STX5 SYTL4 TRIM38 USO1
Entrez ID		6811	6812
HPRD ID		04426	04235
Ensembl ID		ENSG00000162236	ENSG00000136854
Uniprot IDs		B4DKR0 Q13190	P61764
PDB IDs		3EFO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?