SULT2A1 and PRDX4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SULT2A1	PRDX4
Description		sulfotransferase family 2A member 1	peroxiredoxin 4
Image
GO Annotations	Cellular Component	Cytosol	Extracellular Region Cell Nucleus Cytoplasm Endoplasmic Reticulum Smooth Endoplasmic Reticulum Cytosol Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Protein Binding Sulfotransferase Activity Bile-salt Sulfotransferase Activity Steroid Sulfotransferase Activity	Protein Binding Thioredoxin Peroxidase Activity
	Biological Process	Ethanol Catabolic Process Steroid Metabolic Process Lipid Catabolic Process Regulation Of Lipid Metabolic Process Bile Acid Catabolic Process 3'-phosphoadenosine 5'-phosphosulfate Metabolic Process Sulfation	Response To Oxidative Stress I-kappaB Phosphorylation Spermatogenesis Male Gonad Development Peptidyl-proline Hydroxylation To 4-hydroxy-L-proline Protein Maturation By Protein Folding Extracellular Matrix Organization Cellular Response To Stress Hydrogen Peroxide Catabolic Process Neutrophil Degranulation Cell Redox Homeostasis Oxidation-reduction Process Reactive Oxygen Species Metabolic Process Cellular Oxidant Detoxification Negative Regulation Of Male Germ Cell Proliferation
Pathways		Cytosolic sulfonation of small molecules PPARA activates gene expression	Neutrophil degranulation
Drugs		Prasterone Adenosine-3'-5'-Diphosphate Aetiocholanolone Mercuric iodide
Diseases
GWAS		Blood metabolite levels ( 24816252) Blood metabolite ratios ( 24816252) Blood protein levels ( 30072576) Cleft palate ( 30452639) Dehydroepiandrosterone sulphate levels ( 21533175) Gallstone disease ( 30504769 27094239) Serum metabolite levels ( 23093944) Sex hormone levels ( 26014426) Triglyceride levels x long total sleep time interaction (2df test) ( 31719535) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		6 interacting genes: GDF15 PRDX4 STAT3 STK3 SULT1B1 TMX1	25 interacting genes: A1BG ALG12 APOB CFHR1 CFHR3 CLIC1 CYP27A1 DUSP23 GLTPD2 HDAC6 LBP MAP4K2 MT-CO1 NR4A1 PLG PRDX1 PRDX2 PRDX3 RCHY1 SULT2A1 SUMO4 TBXA2R TTF2 UBC VTN
Entrez ID		6822	10549
HPRD ID		00502	05935
Ensembl ID		ENSG00000105398	ENSG00000123131
Uniprot IDs		A8K015 Q06520	Q13162 V9HW63
PDB IDs		1EFH 1J99 1OV4 2QP3 2QP4 3F3Y 4IFB	2PN8 3TJB 3TJF 3TJG 3TJJ 3TJK 3TKP 3TKQ 3TKR 3TKS 4RQX 5HQP
Enriched GO Terms of Interacting Partners?
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