STXBP1 and APBA2

Number of citations of the paper that reports this interaction (PubMedID 9395480)
78

Data Source:
HPRD (two hybrid, in vivo, in vitro)

		STXBP1	APBA2
Description		syntaxin binding protein 1	amyloid beta precursor protein binding family A member 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Mitochondrion Cytosol Cytoskeleton Plasma Membrane Axon Platelet Alpha Granule Protein-containing Complex Phagocytic Vesicle Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Extracellular Exosome Postsynapse Glutamatergic Synapse	Cytoplasm Plasma Membrane Synaptic Vesicle Dendritic Spine Synapse Schaffer Collateral - CA1 Synapse
	Molecular Function	SNARE Binding RNA Binding Protein Binding Syntaxin-1 Binding Protein Kinase Binding Protein Domain Specific Binding Syntaxin Binding Identical Protein Binding Phospholipase Binding Protein N-terminus Binding	Amyloid-beta Binding Protein Binding Identical Protein Binding
	Biological Process	Platelet Degranulation Developmental Process Involved In Reproduction Vesicle Docking Involved In Exocytosis Neurotransmitter Secretion Neuromuscular Synaptic Transmission Axon Target Recognition Regulation Of Synaptic Vesicle Priming Glutamate Secretion Protein Transport Synaptic Vesicle Priming Synaptic Vesicle Maturation Negative Regulation Of Protein Complex Assembly Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Negative Regulation Of Synaptic Transmission, GABAergic Response To Estradiol SNARE Complex Assembly Regulation Of SNARE Complex Assembly Positive Regulation Of Mast Cell Degranulation Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Calcium Ion-dependent Exocytosis Protein Stabilization Long-term Synaptic Depression Platelet Aggregation Cellular Response To Interferon-gamma Protein Localization To Plasma Membrane Presynaptic Dense Core Vesicle Exocytosis Positive Regulation Of Vesicle Docking Positive Regulation Of Glutamate Secretion, Neurotransmission Regulation Of Acrosomal Vesicle Exocytosis	In Utero Embryonic Development Chemical Synaptic Transmission Nervous System Development Locomotory Behavior Regulation Of Gene Expression Protein Transport Multicellular Organism Growth Regulation Of Synaptic Vesicle Exocytosis
Pathways		Regulation of insulin secretion Neurexins and neuroligins	Neurexins and neuroligins
Drugs
Diseases		Early infantile epileptic encephalopathy; Ohtahara syndrome
GWAS		Whole brain grey matter density ( 31530798)	Response to mTOR inhibitor (rapamycin) ( 24009623) Skin pigmentation (conditioned on rs1426654 and rs35397) ( 31315583) Temperament ( 22832960)
Interacting Genes		31 interacting genes: APBA1 APBA2 APP C19orf57 CDK5 CDK5R1 DOC2A DOC2B HGS MAPT MEOX2 MTDH MTNR1A NEFH NEFM PLD1 PLD2 PRKCA PRKCB PRKCG SPTBN1 SQSTM1 STOM STX1A STX1B STX2 STX3 STX5 SYTL4 TRIM38 USO1	13 interacting genes: APP ARF3 ARF4 CLSTN1 CLSTN3 LRP1 LRP2 LRP8 MAPK6 NECAB3 NRXN1 RELA STXBP1
Entrez ID		6812	321
HPRD ID		04235	04090
Ensembl ID		ENSG00000136854	ENSG00000034053
Uniprot IDs		P61764	Q59G28 Q99767
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?