STX4 and SNAP29

Number of citations of the paper that reports this interaction (PubMedID 9852078)
68

Data Source:
BioGRID (pull down)

		STX4	SNAP29
Description		syntaxin 4	synaptosome associated protein 29
Image		No pdb structure
GO Annotations	Cellular Component	Storage Vacuole Extracellular Space Endosome Vacuole Trans-Golgi Network Cytosol Plasma Membrane Synaptic Vesicle Cell Surface Endomembrane System Membrane Integral Component Of Membrane Basolateral Plasma Membrane Lamellipodium Phagocytic Vesicle Membrane SNARE Complex Myelin Sheath Adaxonal Region Somatodendritic Compartment Specific Granule Presynaptic Membrane Dendritic Spine Lateral Loop Synapse Perinuclear Region Of Cytoplasm Presynaptic Active Zone Membrane Extracellular Exosome Postsynapse Glutamatergic Synapse	Golgi Membrane Autophagosome Membrane Cell Nucleoplasm Cytoplasm Autophagosome Centrosome Cytosol Plasma Membrane Ciliary Pocket Membrane SNARE Complex Azurophil Granule Membrane Presynapse
	Molecular Function	SNARE Binding SNAP Receptor Activity Protein Binding Sphingomyelin Phosphodiesterase Activator Activity	SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Intracellular Protein Transport Exocytosis Post-Golgi Vesicle-mediated Transport Vesicle Fusion Positive Regulation Of Cell Proliferation Regulation Of Exocytosis Cytokine-mediated Signaling Pathway Positive Regulation Of Cell Migration Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Cellular Response To Oxidative Stress SNARE Complex Assembly Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Catalytic Activity Positive Regulation Of Eosinophil Degranulation Positive Regulation Of Cell Adhesion Vesicle Docking Organelle Fusion Positive Regulation Of Chemotaxis Positive Regulation Of Immunoglobulin Secretion Long-term Synaptic Potentiation Cellular Response To Interferon-gamma Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Protein Localization To Plasma Membrane Cornified Envelope Assembly Vesicle Fusion With Endoplasmic Reticulum-Golgi Intermediate Compartment (ERGIC) Membrane Positive Regulation Of Protein Localization To Cell Surface	Exocytosis Vesicle Targeting Vesicle Fusion Protein Transport Synaptic Vesicle Priming Autophagosome Membrane Docking Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Neutrophil Degranulation Cilium Assembly Membrane Fusion Autophagosome Maturation
Pathways		Disinhibition of SNARE formation ER-Phagosome pathway Translocation of SLC2A4 (GLUT4) to the plasma membrane trans-Golgi Network Vesicle Budding Other interleukin signaling	Neutrophil degranulation Intra-Golgi traffic
Drugs
Diseases			Cerebral dysgenesis, neuropathy, ichthyosis, and palmoplantar keratoderma syndrome; CEDNIK syndrome
GWAS		Response to metformin (IC50) ( 28173075)
Interacting Genes		48 interacting genes: ACTB BET1 CYBRD1 DLG1 DNAJC5 EMD GIMAP5 GOSR2 ITSN2 LLGL1 LMNA NAPA NAPB NSF PSMA3 RAB11A RAB4A RAB5A SCRIB SEC22A SEPTIN5 SH3GLB2 SNAP23 SNAP25 SNAP29 SNAP47 STX16 STX3 STX5 STX8 STXBP3 STXBP4 STXBP5 STXBP6 SYT1 SYT4 SYT7 TXLNA TXLNB TXLNG VAMP1 VAMP2 VAMP3 VAMP4 VAMP7 VAMP8 VAPB VTI1B	22 interacting genes: AP2A1 ATF4 CD7 DNAJC5 EHD1 EHD3 FAM9B ITSN2 KIFC3 LURAP1 RASSF7 STX12 STX17 STX1A STX3 STX4 STX6 STX7 VAMP1 VAMP2 VAMP4 VAMP7
Entrez ID		6810	9342
HPRD ID		01722	11968
Ensembl ID		ENSG00000103496	ENSG00000099940
Uniprot IDs		B7Z425 Q12846	O95721
PDB IDs			4WY4
Enriched GO Terms of Interacting Partners?
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