STAR and NUCB2

Number of citations of the paper that reports this interaction (PubMedID 12909641)
5

Data Source:
BioGRID (two hybrid)

		STAR	NUCB2
Description		steroidogenic acute regulatory protein	nucleobindin 2
Image			No pdb structure
GO Annotations	Cellular Component	Cell Mitochondrion Mitochondrial Intermembrane Space Cytosol Mitochondrial Crista Neuron Projection Neuronal Cell Body	Extracellular Space Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding Cholesterol Binding Intermembrane Cholesterol Transfer Activity	G-protein Alpha-subunit Binding DNA Binding Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding
	Biological Process	Steroid Biosynthetic Process Bile Acid Biosynthetic Process C21-steroid Hormone Biosynthetic Process Estrogen Biosynthetic Process Brain Development Response To Nutrient Cholesterol Metabolic Process Glucocorticoid Metabolic Process Male Gonad Development Response To Herbicide Response To Ionizing Radiation Response To Lead Ion Positive Regulation Of Gene Expression Response To Activity Diterpenoid Metabolic Process Insecticide Metabolic Process Biphenyl Metabolic Process Dibenzo-p-dioxin Metabolic Process Phenol-containing Compound Metabolic Process Phthalate Metabolic Process Intracellular Cholesterol Transport Cellular Response To Insulin Stimulus Response To Nicotine Cellular Response To Interferon-alpha Response To Hydrogen Peroxide Circadian Sleep/wake Cycle, REM Sleep Negative Regulation Of Neuron Apoptotic Process Response To Estrogen Response To Leptin Cellular Response To Fibroblast Growth Factor Stimulus Response To Ethanol Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Neurogenesis Regulation Of Steroid Biosynthetic Process Response To Corticosterone Response To Fungicide Testosterone Biosynthetic Process Positive Regulation Of Bile Acid Biosynthetic Process Cellular Response To Lipopolysaccharide Cellular Response To Antibiotic Cellular Response To Cadmium Ion Cellular Response To Alkaloid Cellular Response To CAMP Cellular Response To Glucose Stimulus Cellular Response To Interferon-gamma Cellular Response To Follicle-stimulating Hormone Stimulus Cellular Response To Luteinizing Hormone Stimulus Cellular Response To Growth Hormone Stimulus Cellular Response To Dexamethasone Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To Epinephrine Stimulus	Small GTPase Mediated Signal Transduction Negative Regulation Of Appetite
Pathways		Pregnenolone biosynthesis
Drugs			Calcium Citrate Calcium Phosphate
Diseases		46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS) Congenital adrenal hyperplasia (CAH)
GWAS		Menopause (age at onset) ( 26414677) Orthostatic hypotension ( 24124408) Schizophrenia ( 29483656)	Blood protein levels ( 29875488) Body mass index ( 26426971) Height ( 20881960) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 28739976) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500)
Interacting Genes		6 interacting genes: CCHCR1 FEZ1 LIPE MAGEA11 MAPK3 NUCB2	8 interacting genes: GADD45A GNAI3 GNAS NDN NR1I2 SMARCD1 STAR XPO1
Entrez ID		6770	4925
HPRD ID		02794	09726
Ensembl ID		ENSG00000147465	ENSG00000070081
Uniprot IDs		P49675 Q6IBK0	P80303 Q2L696
PDB IDs		1IMG 2I93 3P0L 5OMA
Enriched GO Terms of Interacting Partners?
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