NUCB2 and STAR

Number of citations of the paper that reports this interaction (PubMedID 12909641)
5

Data Source:
BioGRID (two hybrid)

		NUCB2	STAR
Description		nucleobindin 2	steroidogenic acute regulatory protein
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nuclear Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Plasma Membrane Extracellular Exosome	Cell Mitochondrion Mitochondrial Intermembrane Space Cytosol Mitochondrial Crista Neuron Projection Neuronal Cell Body
	Molecular Function	G-protein Alpha-subunit Binding DNA Binding Guanyl-nucleotide Exchange Factor Activity Calcium Ion Binding Protein Binding	Protein Binding Cholesterol Binding Intermembrane Cholesterol Transfer Activity
	Biological Process	Small GTPase Mediated Signal Transduction Negative Regulation Of Appetite	Steroid Biosynthetic Process Bile Acid Biosynthetic Process C21-steroid Hormone Biosynthetic Process Estrogen Biosynthetic Process Brain Development Response To Nutrient Cholesterol Metabolic Process Glucocorticoid Metabolic Process Male Gonad Development Response To Herbicide Response To Ionizing Radiation Response To Lead Ion Positive Regulation Of Gene Expression Response To Activity Diterpenoid Metabolic Process Insecticide Metabolic Process Biphenyl Metabolic Process Dibenzo-p-dioxin Metabolic Process Phenol-containing Compound Metabolic Process Phthalate Metabolic Process Intracellular Cholesterol Transport Cellular Response To Insulin Stimulus Response To Nicotine Cellular Response To Interferon-alpha Response To Hydrogen Peroxide Circadian Sleep/wake Cycle, REM Sleep Negative Regulation Of Neuron Apoptotic Process Response To Estrogen Response To Leptin Cellular Response To Fibroblast Growth Factor Stimulus Response To Ethanol Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Neurogenesis Regulation Of Steroid Biosynthetic Process Response To Corticosterone Response To Fungicide Testosterone Biosynthetic Process Positive Regulation Of Bile Acid Biosynthetic Process Cellular Response To Lipopolysaccharide Cellular Response To Antibiotic Cellular Response To Cadmium Ion Cellular Response To Alkaloid Cellular Response To CAMP Cellular Response To Glucose Stimulus Cellular Response To Interferon-gamma Cellular Response To Follicle-stimulating Hormone Stimulus Cellular Response To Luteinizing Hormone Stimulus Cellular Response To Growth Hormone Stimulus Cellular Response To Dexamethasone Stimulus Cellular Response To Transforming Growth Factor Beta Stimulus Cellular Response To Epinephrine Stimulus
Pathways			Pregnenolone biosynthesis
Drugs		Calcium Citrate Calcium Phosphate
Diseases			46,XY disorders of sex development (Disorders in androgen synthesis or action), including: Congenital adrenal hyperplasias; Leydig cell hypoplasia; Androgen insensitivity syndrome (AIS) Congenital adrenal hyperplasia (CAH)
GWAS		Blood protein levels ( 29875488) Body mass index ( 26426971) Height ( 20881960) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878 28739976) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500)	Menopause (age at onset) ( 26414677) Orthostatic hypotension ( 24124408) Schizophrenia ( 29483656)
Interacting Genes		8 interacting genes: GADD45A GNAI3 GNAS NDN NR1I2 SMARCD1 STAR XPO1	6 interacting genes: CCHCR1 FEZ1 LIPE MAGEA11 MAPK3 NUCB2
Entrez ID		4925	6770
HPRD ID		09726	02794
Ensembl ID		ENSG00000070081	ENSG00000147465
Uniprot IDs		P80303 Q2L696	P49675 Q6IBK0
PDB IDs			1IMG 2I93 3P0L 5OMA
Enriched GO Terms of Interacting Partners?
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