SRP19 and KPNA1

Number of citations of the paper that reports this interaction (PubMedID 11682607)
18

Data Source:
HPRD (in vitro)

		SRP19	KPNA1
Description		signal recognition particle 19	karyopherin subunit alpha 1
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GO Annotations	Cellular Component	Nucleolus Signal Recognition Particle, Endoplasmic Reticulum Targeting Cytosol Signal Recognition Particle	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Dendrite Host Cell Glutamatergic Synapse
	Molecular Function	RNA Binding Protein Binding 7S RNA Binding Ribosome Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition Response To Drug	Regulation Of DNA Recombination Apoptotic DNA Fragmentation NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Process Intracellular Transport Of Virus Postsynapse To Nucleus Signaling Pathway
Pathways		SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane	ISG15 antiviral mechanism Apoptosis induced DNA fragmentation Integration of provirus Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Vpr-mediated nuclear import of PICs Inhibition of nitric oxide production
Drugs
Diseases
GWAS			Calcium levels ( 20705733) LDL cholesterol ( 30275531) LDL cholesterol levels ( 28334899) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)
Interacting Genes		10 interacting genes: AP3S1 APP ATG12 IPO5 IPO7 IPO8 KPNA1 MAPK8IP2 SRP54 TNPO1	39 interacting genes: ANP32A ANP32B ARNT BCAR3 CDKN1B CLK4 CRADD CSE1L ELAVL1 EPAS1 FOSL1 GOPC GTF2IRD1 H2BC21 H3-4 HDAC6 HIF1A IL1RAP KPNB1 LEF1 LMO4 MDM2 NOSIP NUP54 NUP62 ORC4 PAX5 PKM RAG1 RANBP2 RUNX1T1 SENP2 SKP2 SRP19 STAT1 STAT3 TAF9 UBR5 USP1
Entrez ID		6728	3836
HPRD ID		01644	02819
Ensembl ID		ENSG00000153037	ENSG00000114030
Uniprot IDs		A0A087WYR0 A0A2U3TZN1 P09132	B3KXZ2 P52294
PDB IDs		1JID 1MFQ 1RY1 2J37 3KTV 4P3E 5M73	2JDQ 3TJ3 4B18
Enriched GO Terms of Interacting Partners?
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