KPNA1 and CLK4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KPNA1	CLK4
Description		karyopherin subunit alpha 1	CDC like kinase 4
Image
GO Annotations	Cellular Component	Nucleus Nuclear Pore Nucleoplasm Cytoplasm Cytosol Postsynaptic Density Dendrite Host Cell Glutamatergic Synapse	Nucleus
	Molecular Function	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity	Protein Serine/threonine Kinase Activity Protein Serine/threonine/tyrosine Kinase Activity Protein Tyrosine Kinase Activity Protein Binding ATP Binding
	Biological Process	Regulation Of DNA Recombination Apoptotic DNA Fragmentation NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Process Intracellular Transport Of Virus Postsynapse To Nucleus Signaling Pathway	Peptidyl-tyrosine Phosphorylation Regulation Of RNA Splicing Protein Autophosphorylation
Pathways		ISG15 antiviral mechanism Apoptosis induced DNA fragmentation Integration of provirus Transport of Ribonucleoproteins into the Host Nucleus NS1 Mediated Effects on Host Pathways Vpr-mediated nuclear import of PICs Inhibition of nitric oxide production
Drugs
Diseases
GWAS		Calcium levels ( 20705733) LDL cholesterol ( 30275531) LDL cholesterol levels ( 28334899) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892)	Urate levels in obese individuals ( 25811787)
Interacting Genes		39 interacting genes: ANP32A ANP32B ARNT BCAR3 CDKN1B CLK4 CRADD CSE1L ELAVL1 EPAS1 FOSL1 GOPC GTF2IRD1 H2BC21 H3-4 HDAC6 HIF1A IL1RAP KPNB1 LEF1 LMO4 MDM2 NOSIP NUP54 NUP62 ORC4 PAX5 PKM RAG1 RANBP2 RUNX1T1 SENP2 SKP2 SRP19 STAT1 STAT3 TAF9 UBR5 USP1	10 interacting genes: CLASRP HSPB2 KPNA1 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 RNF181 SRPK1 UBL5
Entrez ID		3836	57396
HPRD ID		02819	12140
Ensembl ID		ENSG00000114030	ENSG00000113240
Uniprot IDs		B3KXZ2 P52294	Q9HAZ1
PDB IDs		2JDQ 3TJ3 4B18	6FYV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?