SOS1 and PACSIN1

  • Number of citations of the paper that reports this interaction (PubMedID 11352907)
  • 6
  • Data Source:
  • HPRD (in vivo)

SOS1

PACSIN1

Description SOS Ras/Rac guanine nucleotide exchange factor 1 protein kinase C and casein kinase substrate in neurons 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Body mass index ( 29273807 28448500)
  • Body mass index (joint analysis main effects and physical activity interaction) ( 28448500)
  • Body mass index in physically active individuals ( 28448500)
  • Free thyroxine concentration ( 30367059)
  • High density lipoprotein cholesterol levels ( 30498476)
  • Inflammatory bowel disease ( 27569725)
  • Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes 55 interacting genes: ABI1 ABI3 ANXA2 ATP6V1E1 BIN1 CAV1 CD19 CD2AP COPS3 CRK CRKL CSF1R EGFR EPS8 EPS8L1 EPS8L2 ERBB2 ERBB3 ESR1 FGFR1 FRS2 FYN GAB1 GRAP GRB2 HCK HDLBP HRAS ITSN1 ITSN2 LAT2 LCK MAPK1 MAPK3 MUC1 NCK1 NCK2 PACSIN1 PACSIN3 PIK3R2 PLCG1 PTPN11 PTPN6 RANBP9 RIT2 RRAS SH3BP5 SH3KBP1 SHC1 SIRPA SNX18 SNX9 SPTAN1 TNIK ZAP70 24 interacting genes: ANKRD24 ARHGAP17 DNM1 EHBP1 FTH1 GAS7 HTT ITCH JADE2 KAT7 KHDRBS1 MAPT MT-ATP8 PACSIN2 PACSIN3 POT1 RTKN2 SOS1 SPTBN1 SYNJ1 TPM4 TRPV4 WASF2 WASL
Entrez ID 6654 29993
HPRD ID 01681 05936
Ensembl ID ENSG00000115904 ENSG00000124507
Uniprot IDs G5E9C8 Q07889 Q5TZC3 Q9BY11
PDB IDs 1AWE 1BKD 1DBH 1NVU 1NVV 1NVW 1NVX 1Q9C 1XD2 1XD4 1XDV 2II0 3KSY 4NYI 4NYJ 4NYM 4URU 4URV 4URW 4URX 4URY 4URZ 4US0 4US1 4US2 5OVD 5OVE 5OVF 5OVG 5OVH 5OVI 5WFO 5WFP 5WFQ 5WFR 6BVI 6BVJ 6BVK 6BVL 6BVM 6CUO 6CUP 6CUR 6D55 6D56 6D59 6D5E 6D5G 6D5H 6D5J 6D5L 6D5M 6D5V 6D5W 6EPL 6EPM 6EPN 6EPO 6EPP 6F08 3HAH 3HAI 3Q84 3QNI
Enriched GO Terms of Interacting Partners?
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