SON and PEA15

Number of citations of the paper that reports this interaction (PubMedID 24710276)
4

Data Source:
BioGRID (two hybrid)

		SON	PEA15
Description		SON DNA and RNA binding protein	proliferation and apoptosis adaptor protein 15
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Speck	Nucleoplasm Cytosol Microtubule Associated Complex
	Molecular Function	DNA Binding RNA Binding Protein Binding RS Domain Binding	Protein Binding
	Biological Process	Microtubule Cytoskeleton Organization Mitotic Cytokinesis MRNA Processing RNA Splicing Negative Regulation Of Apoptotic Process Regulation Of RNA Splicing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Cell Cycle	DNA Damage Checkpoint MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways			RAF-independent MAPK1/3 activation RAF/MAP kinase cascade
Drugs
Diseases
GWAS		Psoriasis ( 25854761)
Interacting Genes		8 interacting genes: PEA15 PRPF40A SNIP1 SRPK2 TRIP6 VHL YWHAB YWHAG	39 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13
Entrez ID		6651	8682
HPRD ID		01678	04579
Ensembl ID		ENSG00000159140	ENSG00000162734
Uniprot IDs		J3QSZ5 P18583 Q6ZRV7	B1AKZ4 B1AKZ5 Q15121 Q96FS5
PDB IDs			4IZ5 4IZA 6P6B 6P6C
Enriched GO Terms of Interacting Partners?
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