PEA15 and ATP1B3

Number of citations of the paper that reports this interaction (PubMedID 24710276)
4

Data Source:
BioGRID (two hybrid)

		PEA15	ATP1B3
Description		proliferation and apoptosis adaptor protein 15	ATPase Na+/K+ transporting subunit beta 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Microtubule Associated Complex	Cell Plasma Membrane Sodium:potassium-exchanging ATPase Complex Caveola Sperm Flagellum Melanosome Extracellular Exosome
	Molecular Function	Protein Binding	ATPase Activator Activity Sodium:potassium-exchanging ATPase Activity Cation-transporting ATPase Activity ATPase Binding
	Biological Process	DNA Damage Checkpoint MAPK Cascade Activation Of MAPK Activity Apoptotic Process Carbohydrate Transport Response To Morphine Negative Regulation Of Glucose Import Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Cellular Sodium Ion Homeostasis Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Cellular Potassium Ion Homeostasis Positive Regulation Of ATPase Activity Ion Transmembrane Transport Sodium Ion Transmembrane Transport Sodium Ion Export Across Plasma Membrane Protein Stabilization Leukocyte Migration Potassium Ion Transmembrane Transport Protein Localization To Plasma Membrane Membrane Repolarization Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Sodium Ion Export Across Plasma Membrane Positive Regulation Of Potassium Ion Import Regulation Of Cardiac Conduction Potassium Ion Import Across Plasma Membrane
Pathways		RAF-independent MAPK1/3 activation RAF/MAP kinase cascade	Basigin interactions Ion homeostasis Ion transport by P-type ATPases
Drugs
Diseases
GWAS			Blond vs. brown/black hair color ( 30531825) Pulse pressure ( 27841878) Red cell distribution width ( 27863252 28957414) Testicular germ cell tumor ( 26503584) Total hippocampal volume ( 30279459) Waist-hip ratio ( 28552196)
Interacting Genes		39 interacting genes: ABCD4 AK9 AKT1 ATP1B3 CACYBP CAMK2G CASP8 CEP120 COPS5 DNAJB1 DYRK1A FADD HTRA2 KLHL12 L1CAM LUC7L2 MAPK1 MAPK3 MTIF3 OSBPL1A PANK4 PDE4DIP PDPK1 PGM1 PLD1 PLD2 PPP4R3A PRKCA PUS3 RAMAC RPS6KA3 RSL24D1 SNRPG SON TALDO1 TENT4B TERF2IP TJP1 TRAPPC13	10 interacting genes: BAALC BARD1 BRCA1 MYCBP2 NLRP3 PAXIP1 PEA15 TRIM14 UPF2 USP4
Entrez ID		8682	483
HPRD ID		04579	03521
Ensembl ID		ENSG00000162734	ENSG00000069849
Uniprot IDs		B1AKZ4 B1AKZ5 Q15121 Q96FS5	P54709
PDB IDs		4IZ5 4IZA 6P6B 6P6C
Enriched GO Terms of Interacting Partners?
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