SMARCA4 and PBRM1

  • Number of citations of the paper that reports this interaction (PubMedID 12368262)
  • 61
  • Data Source:
  • HPRD (in vivo)

SMARCA4

PBRM1

Description SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 polybromo 1
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Coronary artery disease ( 24262325 30104761)
  • Coronary artery disease or ischemic stroke ( 24262325)
  • Coronary artery disease or large artery stroke ( 24262325)
  • Disorders of lipid metabolism ( 30166351)
  • HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • Inflammatory skin disease ( 25574825)
  • Ischemic stroke ( 29531354)
  • LDL cholesterol ( 21347282)
  • LDL cholesterol levels ( 30698716)
  • LDL cholesterol levels in current drinkers ( 30698716)
  • LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716)
  • LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716)
  • Medication use (HMG CoA reductase inhibitors) ( 31015401)
  • Multiple sclerosis ( 31604244)
  • Stroke ( 29531354)
  • Autism spectrum disorder or schizophrenia ( 28540026)
  • Bipolar disorder ( 21926972 31043756)
  • Bipolar disorder with mood-incongruent psychosis ( 23092984)
  • Blood protein levels ( 29875488)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • General cognitive ability ( 29844566)
  • Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566)
  • Intelligence (MTAG) ( 29326435)
  • Major mood disorders ( 20081856)
  • Schizophrenia ( 28991256 25056061 29483656 30285260 23974872)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for body mass index ( 28448500)
  • Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500)
  • Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500)
  • Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes 78 interacting genes: ACTB ACTL6A AHR AR ARID1A ARID1B ARID2 BRCA1 BRWD1 CARM1 CBX5 CCNE1 CDK19 CDK8 CDKN2A CDX2 CEBPA CEBPB CHD4 CHFR CHMP5 CIITA CREB1 CTNNB1 E2F6 ESR1 ETS2 FANCA GATA1 GMNN H2AX H2BC21 H3-3A H3C1 H3C14 H4C6 HSF1 HSF4 HSPB1 IKZF1 KLF1 MBD3 MDM2 MED17 MED6 MPHOSPH6 MPP6 MRTFA MYC MYOCD NR3C1 NR4A2 PABPN1 PAX6 PBRM1 PHB RAP1A RASSF1 RB1 RBL1 RBL2 RELB RFXAP SIN3A SIN3B SMARCB1 SMARCC1 SMARCE1 SOX4 SS18 SS18L1 STAT2 STAT3 STK11 TAF15 TMF1 TP53 ZMYND11 9 interacting genes: APP H2AC20 H2BC21 H3C1 H4C1 PTS SMARCA4 ZDHHC17 ZNF512B
Entrez ID 6597 55193
HPRD ID 04459 07302
Ensembl ID ENSG00000127616 ENSG00000163939
Uniprot IDs A7E2E1 B3KNW7 P51532 Q9HBD4 Q86U86
PDB IDs 2GRC 2H60 3UVD 5DKD 5EA1 6BGH 6HR2 2KTB 3G0J 3HMF 3IU5 3IU6 3K2J 3LJW 3MB4 3TLP 4Q0N 4Q0O 4Y03 5E7D 5FH6 5FH7 5FH8 5HRV 5HRW 5HRX 5II1 5II2 5IID
Enriched GO Terms of Interacting Partners?
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