PBRM1 and ZNF512B

Number of citations of the paper that reports this interaction (PubMedID 15231748)
85

Data Source:
BioGRID (two hybrid)

		PBRM1	ZNF512B
Description		polybromo 1	zinc finger protein 512B
Image
GO Annotations	Cellular Component	Nuclear Chromosome Nucleoplasm RSC-type Complex SWI/SNF Superfamily-type Complex	Nucleus
	Molecular Function	DNA Binding Chromatin Binding Protein Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Mitotic Cell Cycle Nucleosome Disassembly Chromatin Remodeling Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Cell Proliferation ATP-dependent Chromatin Remodeling
Pathways		RMTs methylate histone arginines RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 21926972 31043756) Bipolar disorder with mood-incongruent psychosis ( 23092984) Blood protein levels ( 29875488) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) General cognitive ability ( 29844566) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Intelligence (MTAG) ( 29326435) Major mood disorders ( 20081856) Schizophrenia ( 28991256 25056061 29483656 30285260 23974872) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)	Birth weight ( 31043758) Offspring birth weight ( 31043758) Prostate cancer ( 23535732)
Interacting Genes		9 interacting genes: APP H2AC20 H2BC21 H3C1 H4C1 PTS SMARCA4 ZDHHC17 ZNF512B	60 interacting genes: ANKLE2 ANKRD28 AP1G1 APLP2 ATRX BRD1 BTBD2 CDC123 CREBZF CTBP2 DCTN1 DDX3X DROSHA DVL3 EHMT2 FHL3 GLRX3 HEYL HTATSF1 IL36RN INVS KDM2A KDM3B KLF10 KMT2B L1TD1 LAMB2 LZTS2 MBD1 MYH10 NIBAN2 OS9 PAPPA2 PBRM1 PDE4DIP PEG10 PIAS4 PLCG2 PPP1R15A PTPRF RPS27A SDF4 SIAH1 SMAD1 SPTBN1 SUPT5H TGM2 TNKS2 TOM1 TOX4 TRAF1 TRAF4 VHL VPS35 VPS41 VWF XPC XRCC6 YES1 ZMYM2
Entrez ID		55193	57473
HPRD ID		07302	13840
Ensembl ID		ENSG00000163939	ENSG00000196700
Uniprot IDs		Q86U86	Q96KM6
PDB IDs		2KTB 3G0J 3HMF 3IU5 3IU6 3K2J 3LJW 3MB4 3TLP 4Q0N 4Q0O 4Y03 5E7D 5FH6 5FH7 5FH8 5HRV 5HRW 5HRX 5II1 5II2 5IID	2GQJ
Enriched GO Terms of Interacting Partners?
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