SLC12A2 and OXSR1

Number of citations of the paper that reports this interaction (PubMedID 16669787)
92

Data Source:
HPRD (in vitro)

		SLC12A2	OXSR1
Description		solute carrier family 12 member 2	oxidative stress responsive kinase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cell Cytosol Plasma Membrane Integral Component Of Plasma Membrane Membrane Apical Plasma Membrane Extracellular Exosome Extracellular Vesicle	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Protein Binding Sodium:potassium:chloride Symporter Activity Ammonium Transmembrane Transporter Activity Sodium Ion Transmembrane Transporter Activity Sodium:chloride Symporter Activity Potassium:chloride Symporter Activity Protein Kinase Binding	Magnesium Ion Binding Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Protein Kinase Binding Identical Protein Binding
	Biological Process	Ion Transport Cell Volume Homeostasis Hyperosmotic Response Gamma-aminobutyric Acid Signaling Pathway Aging T Cell Chemotaxis Ammonium Transport Transepithelial Chloride Transport Sodium Ion Transmembrane Transport Positive Regulation Of Cell Volume Chloride Ion Homeostasis Potassium Ion Homeostasis Sodium Ion Homeostasis Transepithelial Ammonium Transport Ammonium Transmembrane Transport Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane Cellular Response To Chemokine	Protein Phosphorylation Response To Oxidative Stress Osmosensory Signaling Pathway Regulation Of Mitotic Cell Cycle Positive Regulation Of T Cell Chemotaxis Peptidyl-threonine Phosphorylation Signal Transduction By Protein Phosphorylation Signal Transduction By Trans-phosphorylation Stress-activated Protein Kinase Signaling Cascade Activation Of Protein Kinase Activity Intracellular Signal Transduction Chemokine (C-C Motif) Ligand 21 Signaling Pathway Chemokine (C-X-C Motif) Ligand 12 Signaling Pathway Protein Autophosphorylation Cellular Hypotonic Response Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Cellular Response To Chemokine
Pathways		Cation-coupled Chloride cotransporters
Drugs		Potassium Chloride Bumetanide Quinethazone
Diseases
GWAS		Beard thickness ( 26926045) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain imaging in schizophrenia (dorsolateral prefrontal cortex interaction) ( 19023125) Height ( 25282103 31562340) Ileal carcinoids ( 21139019) Red cell distribution width ( 28957414) Statin-induced myopathy ( 31220337)	Gut microbiota (bacterial taxa) ( 27723756) Mean corpuscular hemoglobin concentration ( 29403010)
Interacting Genes		3 interacting genes: COMMD1 OXSR1 STK39	10 interacting genes: APP BMPR1B GORASP1 PAK1 RELL1 SLC12A1 SLC12A2 SLC12A6 SMURF1 TGFBR1
Entrez ID		6558	9943
HPRD ID		06775	06809
Ensembl ID		ENSG00000064651	ENSG00000172939
Uniprot IDs		B7ZM24 P55011 Q53ZR1	O95747
PDB IDs			2V3S 2VWI 3DAK
Enriched GO Terms of Interacting Partners?
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