UPF3B and MAGOH

Number of citations of the paper that reports this interaction (PubMedID 22961380)
33

Data Source:
BioGRID (pull down)

		UPF3B	MAGOH
Description		UPF3B regulator of nonsense mediated mRNA decay	mago homolog, exon junction complex subunit
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Centriolar Satellite Exon-exon Junction Complex	Nucleus Nucleoplasm Cytoplasm Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding MRNA Binding Protein Binding Structural Constituent Of Nuclear Pore	RNA Binding Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Positive Regulation Of Translation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Translation RNA Splicing MRNA 3'-end Processing
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases		Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS
Interacting Genes		13 interacting genes: EIF4A3 EIF6 EXOSC4 HBB MAGOH MCRS1 RBBP6 RBM8A SRPK2 TTC19 UPF1 UPF2 XRN1	12 interacting genes: ALYREF CORO1A EIF4A3 GOLGA2 IPO13 MAP1B NXF1 RBM8A TADA2A UPF3B XIST YWHAQ
Entrez ID		65109	4116
HPRD ID		02247	04005
Ensembl ID		ENSG00000125351	ENSG00000162385
Uniprot IDs		Q9BZI7	P61326
PDB IDs		1UW4 2XB2	1P27 2HYI 2J0Q 2J0S 2XB2 3EX7
Enriched GO Terms of Interacting Partners?
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