UPF3B

Description		UPF3B regulator of nonsense mediated mRNA decay
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Centriolar Satellite Exon-exon Junction Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Positive Regulation Of Translation
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases		Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS
Interacting Genes		13 interacting genes: EIF4A3 EIF6 EXOSC4 HBB MAGOH MCRS1 RBBP6 RBM8A SRPK2 TTC19 UPF1 UPF2 XRN1
Entrez ID		65109
HPRD ID		02247
Ensembl ID		ENSG00000125351
Uniprot IDs		Q9BZI7
PDB IDs		1UW4 2XB2
Enriched GO Terms of Interacting Partners?
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