ACD and FKBP6

Number of citations of the paper that reports this interaction (PubMedID 21044950)
41

Data Source:
BioGRID (two hybrid)

		ACD	FKBP6
Description		ACD shelterin complex subunit and telomerase recruitment factor	FKBP prolyl isomerase 6
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GO Annotations	Cellular Component	Nuclear Telomere Cap Complex Nuclear Chromosome, Telomeric Region Nucleoplasm Nuclear Body Shelterin Complex	Synaptonemal Complex Cytoplasm Cytosol
	Molecular Function	Protein Binding Telomeric DNA Binding Protein-containing Complex Binding DNA Polymerase Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding Identical Protein Binding Hsp90 Protein Binding
	Biological Process	Telomere Maintenance Intracellular Protein Transport Telomere Capping Protection From Non-homologous End Joining At Telomere Telomere Assembly Negative Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Telomerase Activity Positive Regulation Of Single-stranded Telomeric DNA Binding Protein Localization To Chromosome, Telomeric Region Establishment Of Protein Localization To Telomere	Protein Peptidyl-prolyl Isomerization Protein Folding Spermatogenesis Cell Differentiation Gene Silencing By RNA PiRNA Metabolic Process DNA Methylation Involved In Gamete Generation Positive Regulation Of Viral Genome Replication Meiotic Cell Cycle
Pathways		Recognition and association of DNA glycosylase with site containing an affected pyrimidine Cleavage of the damaged pyrimidine Recognition and association of DNA glycosylase with site containing an affected purine Recognition and association of DNA glycosylase with site containing an affected purine Cleavage of the damaged purine Cleavage of the damaged purine Meiotic synapsis Packaging Of Telomere Ends Telomere Extension By Telomerase DNA Damage/Telomere Stress Induced Senescence	Meiotic synapsis PIWI-interacting RNA (piRNA) biogenesis
Drugs
Diseases
GWAS		Schizophrenia ( 25056061 29483656)	Height ( 31562340) Immune reponse to smallpox (secreted IL-12p40) ( 22610502)
Interacting Genes		60 interacting genes: ACTB ADPRH AFAP1L2 AIPL1 ANKMY2 ANXA8L1 APOBEC3F BAG3 CKB CTTN DBN1 DBNL DCX DPYSL3 EIF3G EIF4B ENO2 ENSA FAM131B FKBP6 GAPDH HSP90AB1 IPO5 IVL LASP1 LDHA LGALSL LLGL1 LRRC25 NCDN NUDC NUDCD2 PAGE2 PDLIM2 PEX5 PFKP PGM2 POT1 RBKS RECQL4 RGS3 RPSA SBDS STIP1 STUB1 SULT1C2 TAGLN TBC1D10A TBCD TINF2 TOMM34 TRIM15 TRIM16 TUBB2A TUBB4B USP7 XRCC6 YWHAE ZFP36L1 ZNF790	13 interacting genes: ACD CCNK CDK5RAP3 FAM107A GAPDH HSP90AA1 IHO1 LZTS2 MAP3K1 MEOX2 NME7 SUMO1P1 TINF2
Entrez ID		65057	8468
HPRD ID		12417	05326
Ensembl ID		ENSG00000102977	ENSG00000077800
Uniprot IDs		A0A590TQL1 A0A5F9ZCY9 Q96AP0	A0A3B3IST2 O75344
PDB IDs		2I46 5H65 5I2X 5I2Y 5UN7 5XYF	3B7X
Enriched GO Terms of Interacting Partners?
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