BMP2 and TGFB2

  • Number of citations of the paper that reports this interaction (PubMedID 9493905)
  • 22
  • Data Source:
  • HPRD (in vivo)

BMP2

TGFB2

Description bone morphogenetic protein 2 transforming growth factor beta 2
Image
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Acne (severe) ( 24927181 30542056)
  • Body fat distribution (leg fat ratio) ( 30664634)
  • Body fat distribution (trunk fat ratio) ( 30664634)
  • Bone mineral density (hip) ( 30172743)
  • Central corneal thickness ( 29760442)
  • Chronic obstructive pulmonary disease ( 28166215 30804561)
  • Chronic obstructive pulmonary disease (severe) ( 24621683)
  • Diastolic blood pressure ( 30224653)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Emphysema imaging phenotypes ( 26030696)
  • FEV1 ( 30804560)
  • Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
  • Heel bone mineral density ( 30598549)
  • Height ( 20881960 25282103 25429064 31562340)
  • Hip circumference adjusted for BMI ( 25673412)
  • Hip minimal joint space width ( 27701424)
  • Intraocular pressure ( 29617998)
  • Local histogram emphysema pattern ( 25006744)
  • Lung function (FEV1/FVC) ( 30804560)
  • Lung function (FVC) ( 30804560)
  • Peak expiratory flow ( 30804560)
  • Post bronchodilator FEV1 ( 26634245)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Pulmonary function ( 21946350)
  • Rosacea symptom severity ( 29771307)
  • Systolic blood pressure ( 30578418)
  • Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993)
  • Vertical cup-disc ratio (multi-trait analysis) ( 31959993)
  • Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625)
  • Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500)
  • Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625)
  • Waist circumference adjusted for BMI in active individuals ( 28448500)
  • Waist circumference adjusted for BMI in non-smokers ( 28443625)
  • Waist circumference adjusted for body mass index ( 25673412 28448500)
Interacting Genes 21 interacting genes: ACTR2 ACVR1 ACVR2A ACVR2B ASCL1 BMPER BMPR1A BMPR1B BMPR2 CHRD CHRDL2 COL2A1 ENG GREM1 GREM2 MGP NOG RGMB SOSTDC1 TGFB1 TGFB2 16 interacting genes: APP BMP2 CCN2 DCN ENG FMOD LTBP3 MARK1 PZP TGFB1 TGFB3 TGFBR1 TGFBR2 TGFBR3 VASN VTN
Entrez ID 650 7042
HPRD ID 00206 01828
Ensembl ID ENSG00000125845 ENSG00000092969
Uniprot IDs C8C060 P12643 P61812 Q59EG9
PDB IDs 1ES7 1REU 1REW 2GOO 2H62 2H64 2QJ9 2QJA 2QJB 3BK3 3BMP 4MID 4N1D 4UHY 4UHZ 4UI0 4UI1 4UI2 6OMN 1TFG 2TGI 4KXZ 5TX4 5TY4 6I9J
Enriched GO Terms of Interacting Partners?
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