HOMEZ and DEF6

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology, affinity chromatography technology)

		HOMEZ	DEF6
Description		homeobox and leucine zipper encoding	DEF6 guanine nucleotide exchange factor
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Filopodium Perinuclear Region Of Cytoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Corepressor Activity	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Height ( 31562340) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)	Height ( 18391951) Systemic lupus erythematosus ( 28714469)
Interacting Genes		37 interacting genes: AEN AXIN1 CENPS DEF6 DGCR6 DNTTIP1 EBF1 EIF4E2 ELOA GRB2 HOXC8 KPNA2 LNX1 LRRC7 MAD2L1BP MED18 MRPL11 NCK1 NCK2 PIN1 PRKAA1 PRKAA2 RBM39 RNF8 RPGR RPL9 SDCBP SH3RF2 SMARCB1 SMYD1 SNRPB2 SUMO2 TEAD4 TLE5 TRAF4 ZBTB7A ZNF688	15 interacting genes: APP BEGAIN CDC42 CDC42EP1 EIF4ENIF1 HOMEZ LCK PBXIP1 PLSCR1 PTK2 RAC1 RAC2 RHOA TCF4 ZAP70
Entrez ID		57594	50619
HPRD ID		12167	10869
Ensembl ID		ENSG00000215271	ENSG00000023892
Uniprot IDs		Q8IX15	Q9H4E7
PDB IDs		2ECC 2YS9
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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