SRSF3 and PCBP1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (affinity chromatography technology, two hybrid)
HPRD (two hybrid)

		SRSF3	PCBP1
Description		serine and arginine rich splicing factor 3	poly(rC) binding protein 1
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Nuclear Speck	Nucleoplasm Cytoplasm Cytosol Membrane Nuclear Speck Cytoplasmic Ribonucleoprotein Granule Extracellular Exosome
	Molecular Function	RNA Binding Protein Binding Phospholipase Binding Sequence-specific MRNA Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Single-stranded DNA Binding RNA Binding MRNA Binding Protein Binding Cadherin Binding Sequence-specific Single Stranded DNA Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing MRNA Cis Splicing, Via Spliceosome Regulation Of MRNA Splicing, Via Spliceosome Cellular Response To Leukemia Inhibitory Factor	MRNA Splicing, Via Spliceosome RNA Metabolic Process Viral RNA Genome Replication Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination	mRNA Splicing - Major Pathway Processing of Capped Intron-Containing Pre-mRNA
Drugs
Diseases
GWAS		Vertical cup-disc ratio (adjusted for vertical disc diameter) ( 31959993) Vertical cup-disc ratio (multi-trait analysis) ( 31959993)	Acne (severe) ( 24927181) Male-pattern baldness ( 28196072)
Interacting Genes		21 interacting genes: APP CHD1 CLK1 EXOSC6 GEMIN2 HNRNPK IL7R NXF1 PCBP1 PCBP2 RBM7 RBMY1A1 SCAF11 SREK1 SRPK1 SRPK2 SRSF2 TRA2B YWHAB YWHAG YWHAQ	42 interacting genes: ANP32A APP CAV3 CELF2 CELF3 ERG EWSR1 FTH1 GNB2 HMGA1 HNRNPD HNRNPK HNRNPLL LMNA MATR3 MOGS NOVA1 PABPC1 PCBP2 PCBP4 PDLIM7 PPIG PPIL3 PRPF3 PTBP1 PUF60 QKI RALY RBFOX2 RBM10 RBM11 RBM14 RBM42 SNRPA SRPK2 SRSF3 TCERG1 TSC22D4 UGP2 ZCCHC10 ZNF384 ZNF830
Entrez ID		6428	5093
HPRD ID		04530	03128
Ensembl ID		ENSG00000112081	ENSG00000169564
Uniprot IDs		B2R6F3 P84103	Q15365 Q53SS8
PDB IDs		2I2Y 2I38	1WVN 1ZTG 3VKE
Enriched GO Terms of Interacting Partners?
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