SET and JUNB

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		SET	JUNB
Description		SET nuclear proto-oncogene	JunB proto-oncogene, AP-1 transcription factor subunit
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Lipid Droplet Cytosol Protein-containing Complex Perinuclear Region Of Cytoplasm	Chromatin Nuclear Chromatin Nucleoplasm Transcription Factor Complex Transcription Factor AP-1 Complex
	Molecular Function	DNA Binding Protein Phosphatase Inhibitor Activity Protein Binding Protein Phosphatase Regulator Activity Histone Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding
	Biological Process	DNA Replication Nucleosome Assembly Nucleosome Disassembly Viral Process Negative Regulation Of Phosphoprotein Phosphatase Activity Negative Regulation Of Histone Acetylation Regulation Of MRNA Stability Negative Regulation Of Neuron Apoptotic Process Negative Regulation Of Transcription, DNA-templated	Negative Regulation Of Transcription By RNA Polymerase II Vasculogenesis Osteoblast Differentiation Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Response To Radiation Response To Mechanical Stimulus Response To Organic Substance Cytokine-mediated Signaling Pathway Osteoclast Differentiation Response To Lipopolysaccharide Cellular Response To Hormone Stimulus Cellular Response To Stress Osteoblast Proliferation Response To Cytokine Regulation Of Cell Proliferation Response To Drug Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Decidualization Response To CAMP Regulation Of Cell Cycle Embryonic Process Involved In Female Pregnancy Labyrinthine Layer Blood Vessel Development Cellular Response To Calcium Ion
Pathways		Condensation of Prophase Chromosomes HuR (ELAVL1) binds and stabilizes mRNA	SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Interleukin-4 and Interleukin-13 signaling NGF-stimulated transcription
Drugs
Diseases
GWAS		Axial length ( 24144296) Body mass index ( 26426971) Eating disorders (purging via substances) ( 23568457)
Interacting Genes		54 interacting genes: ANP32A APEX1 APP CALM1 CDK5 CDK5R1 CDKN1A CHAF1A CHRM2 CHRM3 ELAVL1 ELF4 EP300 ESR1 FAM111B FBXO7 FOS FOXO1 GZMA GZMK H2BC1 H3-3A H3-4 H4-16 H4C14 HMGB2 IRF1 JUNB KLF5 KMT2A LGMN MDM2 MEOX2 MTERF1 NME1 NUCB1 NUPR1 PIK3CG PPP2CA PPP2R1B PRKAR1A PTMA RAC1 SDCBP SETBP1 SGO1 TAF1A TERF1 TERF2 TERF2IP THAP7 TREX1 UCHL5 XRCC6	37 interacting genes: APLP2 ATF4 BATF BATF2 BCL6 BDNF BRCA1 DDIT3 DNMT3L EP300 ESR1 FOS FOSB FOSL1 FOSL2 HOXA7 ITCH JDP2 MAP2 MAPK14 MAPK6 MAPK8 MAPK9 NEU1 NFE2L1 NINL PKIA SAT1 SET SMAD3 SMAD4 SMURF1 TCERG1 TDG USP24 ZNF595 ZSWIM9
Entrez ID		6418	3726
HPRD ID		09023	01303
Ensembl ID		ENSG00000119335	ENSG00000171223
Uniprot IDs		A0A024R895 A0A0C4DFV9 Q01105 Q5VXV3	P17275 Q5U079
PDB IDs		2E50
Enriched GO Terms of Interacting Partners?
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