PKNOX2 and HOXB1

Number of citations of the paper that reports this interaction (PubMedID 11972344)
14

Data Source:
HPRD (in vitro)

		PKNOX2	HOXB1
Description		PBX/knotted 1 homeobox 2	homeobox B1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Actin Cytoskeleton Microtubule Cytoskeleton Intercellular Bridge	Nuclear Chromatin
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Actin Monomer Binding Actin Filament Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Domain Specific Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Regulation Of Transcription, DNA-templated Multicellular Organism Development Pattern Specification Process Anterior/posterior Pattern Specification Rhombomere 4 Development Rhombomere 5 Development Facial Nerve Structural Organization Facial Nucleus Development Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Formation Involved In Morphogenesis Embryonic Skeletal System Morphogenesis
Pathways			Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Alcohol and nicotine co-dependence ( 22488850) Alcohol dependence ( 21956439 21703634) Alcohol dependence symptom count ( 27151647) Alzheimer's disease (survival time) ( 25649651) Breast cancer (survival) ( 25890600) Dimensional psychopathology (Social) ( 29496196) Disease progression in age-related macular degeneration ( 29346644) Formal thought disorder in schizophrenia ( 22648509) Heel bone mineral density ( 30598549) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Prostate cancer ( 29892016) Schizophrenia ( 22688191) Serum uric acid levels in response to allopurinol in gout ( 25676789) Sleep duration ( 25469926) Substance dependence ( 21298047) Testicular germ cell tumor ( 28604728)	Body mass index ( 26426971) Colorectal or endometrial cancer ( 26621817) Primary tooth development (number of teeth) ( 20195514) Waist circumference ( 28552196)
Interacting Genes		1 interacting genes: HOXB1	9 interacting genes: CREBBP EP300 HMGB1 MEIS1 PAX6 PBX1 PKNOX2 RCHY1 SERPINA3
Entrez ID		63876	3211
HPRD ID		17857	00855
Ensembl ID		ENSG00000165495	ENSG00000120094
Uniprot IDs		Q96KN3	P14653
PDB IDs			1B72
Enriched GO Terms of Interacting Partners?
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