HOXB1 and PKNOX2

Number of citations of the paper that reports this interaction (PubMedID 11972344)
14

Data Source:
HPRD (in vitro)

		HOXB1	PKNOX2
Description		homeobox B1	PBX/knotted 1 homeobox 2
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin	Nucleoplasm Cytoplasm Actin Cytoskeleton Microtubule Cytoskeleton Intercellular Bridge
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Domain Specific Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Actin Monomer Binding Actin Filament Binding
	Biological Process	Regulation Of Transcription, DNA-templated Multicellular Organism Development Pattern Specification Process Anterior/posterior Pattern Specification Rhombomere 4 Development Rhombomere 5 Development Facial Nerve Structural Organization Facial Nucleus Development Positive Regulation Of Transcription By RNA Polymerase II Anatomical Structure Formation Involved In Morphogenesis Embryonic Skeletal System Morphogenesis	Regulation Of Transcription By RNA Polymerase II
Pathways		Activation of anterior HOX genes in hindbrain development during early embryogenesis
Drugs
Diseases
GWAS		Body mass index ( 26426971) Colorectal or endometrial cancer ( 26621817) Primary tooth development (number of teeth) ( 20195514) Waist circumference ( 28552196)	Alcohol and nicotine co-dependence ( 22488850) Alcohol dependence ( 21956439 21703634) Alcohol dependence symptom count ( 27151647) Alzheimer's disease (survival time) ( 25649651) Breast cancer (survival) ( 25890600) Dimensional psychopathology (Social) ( 29496196) Disease progression in age-related macular degeneration ( 29346644) Formal thought disorder in schizophrenia ( 22648509) Heel bone mineral density ( 30598549) Obesity-related traits ( 23251661) Photic sneeze reflex ( 27182965) Prostate cancer ( 29892016) Schizophrenia ( 22688191) Serum uric acid levels in response to allopurinol in gout ( 25676789) Sleep duration ( 25469926) Substance dependence ( 21298047) Testicular germ cell tumor ( 28604728)
Interacting Genes		9 interacting genes: CREBBP EP300 HMGB1 MEIS1 PAX6 PBX1 PKNOX2 RCHY1 SERPINA3	1 interacting genes: HOXB1
Entrez ID		3211	63876
HPRD ID		00855	17857
Ensembl ID		ENSG00000120094	ENSG00000165495
Uniprot IDs		P14653	Q96KN3
PDB IDs		1B72
Enriched GO Terms of Interacting Partners?
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